1.
Biochimie
; 57(3): 343-52, 1975.
Article
in English
| MEDLINE
| ID: mdl-1148328
ABSTRACT
The increase above normal in the rate of synthesis of human fetal hemoglobin in incubated cells from adults, as observed previously, is only relative. The addition of serum to the incubation medium tends to reestablish the normal ratio of rates. In the absence of serum the decrease in rates of synthesis affects most strongly the hemoglobin component, whichever it be, that is synthesized more intensively at the cell stage under consideration. This is brought out by the comparison of the effects of different media on fetal and adult cells. The data lead to the definition of the concept of stenogenic and eurygenic states of differentiation.
Subject(s)
Cell Differentiation , Hemoglobins/biosynthesis , Bone Marrow , Cells, Cultured , Culture Media , Cyanogen Bromide , Erythroblasts/metabolism , Female , Fetal Hemoglobin/biosynthesis , Fetus , Gestational Age , Granulocytes/metabolism , Hematopoietic Stem Cells/cytology , Hematopoietic Stem Cells/metabolism , Hemoglobins/analysis , Humans , Hydrolysis , Liver , Lymphocytes/metabolism , Male , Models, Biological , Peptides/analysis , Trypsin
2.
C R Acad Hebd Seances Acad Sci D
; 278(20): 2581-3, 1974 May 13.
Article
in French
| MEDLINE
| ID: mdl-4213535
3.
Biochimie
; 56(4): 554-8, 1974.
Article
in French
| MEDLINE
| ID: mdl-4420371
4.
Biochimie
; 56(4): 547-53, 1974.
Article
in English
| MEDLINE
| ID: mdl-4421269
5.
Bull Soc Chim Biol (Paris)
; 49(12): 1873-8, 1967.
Article
in French
| MEDLINE
| ID: mdl-5582437