In Vitro Antibacterial Activity of Ethanol Extracts of Cinnamomum zeylanicum against Pseudomonas aeruginosa.

Cinnamomum zeylanicum as medicinal plants are measured as new resources for preparing elements in the treatment of antibiotic-resistant microbes as alternatives to antibiotics. This study was aimed to evaluate the antibacterial activity of ethanol extracts of Cinnamomum zeylanicum against a Gram-negative bacteria Pseudomonas aeruginosa. This experimental study was carried out in the department of Pharmacology & Therapeutics and department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh from July 2017 to July 2018. Evaluation of the in vitro antibacterial activity of ethanol extracts of Cinnamomum zeylanicum against Pseudomonas aeruginosa was performed by disc diffusion method. And also in this study we used broth dilution method to determine the minimum inhibitory concentration (MIC). Ethanol cinnamon extract (ECE) was found active against P. aeruginosa. Zone of inhibition (ZOI) ranged between 6-25mm at different concentration of extracts. The MIC was 0.3g/ml. Cinnamomum zeylanicum showed strong antibacterial activity against a Gram-negative bacteria Pseudomonas aeruginosa. The results may contribute to the development of potential antimicrobial agents for inclusion in antipseudomonal regimens.

Relationship of HDL-C and Triglyceride with Hypertension in Adult Men.

Hypertension is a complex disorder involving multiple organ systems and the primary modifiable risk factor for heart disease. Aim of the study was to assess the relationship of serum HDL-C and triglyceride with hypertensive patients in order to compare this parameter with normotensive subjects. This analytical type of cross sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from July 2017 to June 2018. A total number of 120 male subjects, age ranged from 30-65 years was included in this study. Among them, sixty (60) hypertensive subjects were taken as study group (Group II) and sixty (60) ages matched normotensive male subjects were taken as control group (Group I). Data were expressed as mean±SD and statistical significance of difference among the group was calculated by unpaired student's 't' test. In this study we found that serum triglyceride and serum HDL cholesterol were significant in study group in comparison with control group. Therefore, by this study we recommended that routine estimation of these parameters is important for prevention of complication related to hypertension for leading a healthy life.

Relationship of HDL-C and Triglyceride with Type 2 Diabetes Mellitus in Adult Female.

Diabetes mellitus is a complex disorder involving multiple organ systems and is the primary modifiable risk factor for heart disease. Patients with type 2 diabetes mellitus have an increased prevalence of lipid abnormalities. A timely intervention to normalize circulating lipids could decrease the probability of cardiovascular complications. Aim of the study was to assess the relationship of serum High Density Lipoprotein Cholesterol (HDL-C) and triglyceride (TG) with type 2 diabetic patients in order to compare this parameter with non-diabetic subjects. This analytical type of cross sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from July 2017 to June 2018. A total number of 160 female subjects, age ranged from 35-65 years was included in this study. Among them, eighty (80) type 2 diabetic patients were taken as study group (Group II) and eighty (80) ages matched non-diabetic female healthy subjects were taken as control group (Group I). Data were expressed as mean±SD and statistical significance of difference among the group was calculated by student's unpaired (t) test. The mean±SD of serum HDL-C of control group and study group were 49.60±2.18mg/dl & 28.58±2.80mg/dl respectively. In study group serum HDL-C was decreased. The mean±SD of serum Triglyceride of Group I and Group II were 122.06±11.65mg/dl & 221.84±11.79mg/dl respectively. In group II serum triglyceride was increased. Serum HDL cholesterol and serum triglyceride were significant in study group in comparison with control group. Therefore, by this study we recommended that routine estimation of these parameters is important for prevention of complication related to type 2 diabetes mellitus for leading a healthy life.