1.
Ther Drug Monit
; 11(1): 73-8, 1989.
Article
in English
| MEDLINE
| ID: mdl-2643204
ABSTRACT
A recently developed system for measuring antiepileptic drug concentrations was evaluated for phenytoin and phenobarbital. The apoenzyme reactive immunoassay system was compared with gas-liquid chromatography, EMIT, and TDX systems. Comparisons were performed with control specimens and with sera obtained from patients at three facilities. Precision for all methods was similar, with within-run and between-run coefficients of variation generally 5%. The accuracy of all methods was acceptable, but bias was present in some. However, measurements obtained by a nontechnical person (physician) in a clinical setting were sometimes inaccurate.
Subject(s)
Phenobarbital/blood , Phenytoin/blood , Chromatography, Gas , Humans , Immunoenzyme Techniques , Multicenter Studies as Topic
2.
Ind Health Care
; 7: 41-51, 1978.
Article
in English
| MEDLINE
| ID: mdl-10287825