ABSTRACT
Archival materials (medical histories, results of coronary angiography) of 307 patients with coronary artery disease (mean age 57.12 ± 10.04 years) were analyzed. Professional activity of 59 patients was associated with prolonged exposure to industrial hazard (xenobiotics). It was shown that proximal and middle parts of the major epicardial coronary arteries were most susceptible to atherosclerosis. In these segments complete chronic occlusion most often occurred. In one of five patients with coronary artery disease changes in the coronary arteries were not visualized by angiography. Percentage of unaffected coronary arteries was significantly higher in patients who were not in contact with technogenic xenobiotics. The degree of stenosis depended primarily on the effects of harmful occupational exposures, triglyceride, HDLP and LDLP cholesterol levels and hypertension. The number of damages to coronary blood vessels was determined mainly by the age of the patients and the presence of diabetes. The results show the importance of harmful work conditions as a risk factor for atherosclerotic changes in the coronary vessels.
