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Hum Immunol ; 77(10): 818-819, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27370684

ABSTRACT

A total of 951 Southeast Asia Malays from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, there were significant deviation from Hardy-Weinberg proportions for the HLA-A (p<0.0001), -B (p<0.0001), -DRB1 (p<0.0001) and -DQB1 (p<0.01) loci. Minor deviations from HWEP were detected for HLA-C (p=0.01). This genotype data was available in Allele Frequencies Network Database (AFND) Gonzalez-Galarza et al. (2015).


Subject(s)
Ethnicity , HLA-A Antigens/genetics , HLA-B27 Antigen/genetics , HLA-C Antigens/genetics , HLA-DQ beta-Chains/genetics , HLA-DRB1 Chains/genetics , Alleles , Asia, Southeastern , Databases, Nucleic Acid , Gene Frequency , Genetics, Population , Haplotypes , Humans , Malaysia/epidemiology
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