ABSTRACT
In this report we describe the coexpression of T- and B-cell markers on lymphocytes from two patients with B-cell, chronic lymphocytic leukemia. The t-cell markers tested included the sheep red blood cell (SRBC) receptor and the T1 and T11 antigens; the B-cell markers included B4, B1, B2 and Dr (la); surface immunoglobulin IgM, IgD, IgG Kappa and lambda chains. Analysis of the result by independent multiplicative probability showed a minimum coexpression of T- and B-markers on 18.83% and 29.15% of the cells from patients 1 and 2, respectively. Two findings stand out from the result reported here. First, the report documents two additional cases of rare form of CLL. Second, the cases were detected in patients from the state of Zulia, Venezuela, where the incidence of chronic lymphocytic leukemia is low
