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1.
Ann Biomed Eng ; 49(11): 2975-2989, 2021 Nov.
Article in English | MEDLINE | ID: mdl-32975697

ABSTRACT

Military vehicle underbody blast (UBB) is the cause of many serious injuries in theatre today; however, the effects of these chaotic events on the human body are not well understood. The purpose of this research was to replicate UBB loading conditions on the human pelvis and investigate the resulting response in a controlled laboratory setting. In addition to better understanding the response of the human pelvis to high rate vertical loading, this test series also aimed to identify high rate injury thresholds. Twenty-seven post mortem human surrogate (PMHS) component pelvis tests were completed using the University of Virginia's (UVa) simulated blast rig under a range of loading conditions and postures. Of those tests, 17 were in the anteriorly-tilted posture and used to construct the human injury probability curve. Average seat pan (rigid) accelerations for this subset of tests ranged from 300 to 2400 g over 2 to 3 ms of positive phase duration. Post-test computed tomography (CT) scans and necropsies were performed to determine injuries and revealed a frequent occurrence of anterior and posterior injuries, resulting in unstable pelvis ring fractures. The resulting Human Injury Probability Curve (HIPC) yielded mean forces of 5529, 8516, and 12431 N as measured by mass compensated seat platen loadcells applied through the rigid seat to the bilateral ischium are associated with a 10, 25, and 50% risk for unstable pelvic ring sacrum fractures in an anteriorly-tilted pelvis (28° from vertical), respectively.


Subject(s)
Blast Injuries , Pelvis/injuries , Posture , Aged , Aged, 80 and over , Biomechanical Phenomena , Explosions , Humans , Male , Middle Aged , Stress, Mechanical
2.
Traffic Inj Prev ; 14(2): 159-67, 2013.
Article in English | MEDLINE | ID: mdl-23343025

ABSTRACT

OBJECTIVE: The recent refinement of high-rate optical tracking allows dramatically detailed thoracic deformation measurements to be taken during postmortem human subject (PMHS) sled tests. These data allow analysis of restraint belt geometry and the 3-dimensional thoracic deformations generated by belt impingement. One consequence of this new capability is a better understanding of complementary thoracic characterization experiments such as tabletop tests and how the thoracic response can be interpreted for applications involving more complex loading mechanisms. METHODS: This article reports a detailed evaluation of the timing, magnitude, and direction of the applied belt forces and the resulting thoracic deformations in 2 previously performed tests series involving frontal sled tests and tabletop belt-loading tests. RESULTS: In the sled tests, the posteriorly directed component (SAE x) of the belt tension (F(B)) was F(Bx) = 0.70 F(B) at the shoulder but only F(Bx) = 0.14 F(B) where the belt engaged the anterolateral torso inferiorly. The corresponding components on the tabletop were F(Bx) = 0.60 F(B) (shoulder) and F(Bx) = 0.48 F(B) (lower). CONCLUSIONS: When these components are cross-plotted with chest deflection, pronounced consequences of thoracic anterior wall deformation patterns due to flexion of the thoracic spine and the internal viscera's inertia can be seen in the effective thoracic stiffness. Supplemental materials are available for this article. Go to the publisher's online edition of Traffic Injury Prevention to view the supplemental file.


Subject(s)
Accidents, Traffic/statistics & numerical data , Seat Belts/adverse effects , Shoulder/physiology , Thoracic Injuries/etiology , Biomechanical Phenomena , Cadaver , Humans , Male , Weight-Bearing/physiology
3.
Traffic Inj Prev ; 11(2): 194-201, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20373240

ABSTRACT

OBJECTIVE: The neck injury index, NII, developed in ISO 13232 (2005) as a testing and evaluation procedure for assessing the risk of injury to the AO/C1/C2 region of the cervical spine in motorcycle riders is reevaluated using an existing postmortem human subjects (PMHS) data set and resulting in a reformulated NII criterion applicable to PMHS tests. METHODS: A recent series of 36 PMHS head/neck component tests was used to examine the risk of neck injury in frontal impacts and to assess the predictive capability of NII for impacts of various orientations. Using force and moment load cell PMHS experimental data, injury risk was assessed using NII evaluated with the ISO 13232-5 algorithms. RESULTS: The injury risk predictions are compared with the injury outcomes from the head/neck PMHS. The NII criterion underestimated the injury incidence of the PMHS experimental group. The average predicted risk of injuries for the experimental injury tests based on NII across the MAIS levels was 0.7 percent, though there were 11 AIS 3+ injuries observed in the actual testing (30.6%). Using the experimental injury outcomes and the experimental force and moment time histories, the normalizing coefficients from NII are reevaluated to minimize the difference between NII risk assessment and the experimental injury outcome in the least squares (L(2)) basis. This reanalysis is compared with existing human and PMHS neck injury criteria. CONCLUSIONS: By reanalyzing the NII formulation using an existing PMHS injury data set with known forces and moments and known injury outcomes, a new NII(PMHS) is developed that uses PMHS loads to predict injury. This reformulation removes the dependency of the original NII formulation on the forces and moments from motorcyclist anthropomorphic test device (MATD) experiments and simulations yet retains the advantages of the multi-axial neck injury criterion.


Subject(s)
Accidents, Traffic , Cervical Vertebrae/injuries , Motorcycles , Neck Injuries , Risk Assessment/methods , Trauma Severity Indices , Algorithms , Humans , Least-Squares Analysis , Normal Distribution , Survival Analysis
4.
Traffic Inj Prev ; 10(3): 290-6, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19452371

ABSTRACT

OBJECTIVE: Three postmortem human surrogates (PMHS) were positioned and rigidly mounted through the spine to a tabletop test fixture for the purpose of characterizing thoracic response to diagonal belt loading with well-defined boundary conditions. METHODS: These PMHS were mounted to a stationary apparatus that supported the spine and shoulders in a configuration comparable to that seen in a 48 km/h automobile sled test at the time of maximum chest deformation. A belt restraint was positioned across the anterior torso with attachments at D-ring and buckle locations based on the geometry of a mid-sized sedan. The belt was attached to a trolley driven by a hydraulic ram linked to a universal test machine. Ramp and hold experiments were conducted at rates of 0.5, 0.9, and 1.2 m/s and hold times of 60 s. Ramp-hold displacement waveforms of up to 20 percent of the chest depth were applied to the chest while the resulting belt loads and spinal reaction loads were recorded. These data were used to identify parameters in a seven-parameter thoracic structural model mathematically analogous to a viscoelastic material model. A final test with 40 percent deflection was performed at the completion of the loading sequence. RESULTS: Model fits to ramps of different magnitudes indicated that the assumption of temporal linearity was reasonable over the range of inputs in this study. In agreement with previous studies, the spatial (force-deflection) response was only slightly nonlinear, indicating that a fully linear model would be reasonable up to the deflection levels used here. CONCLUSIONS: Pronounced variability in the instantaneous elastic behavior was observed among the three test subjects, whereas the relaxation behavior exhibited less variability.


Subject(s)
Elasticity/physiology , Seat Belts , Thorax , Algorithms , Cadaver , Humans , Male , Middle Aged , Models, Biological , Spine
5.
J Biomech ; 28(11): 1333-40, 1995 Nov.
Article in English | MEDLINE | ID: mdl-8522546

ABSTRACT

A possible correlation between regions of high intramural wall stress and the development of atherosclerotic lesions in the carotid artery bifurcation is investigated. The bifurcation geometry is determined through in vivo studies, as well as the analysis of cadaver specimens. Having compiled accurate geometric data, two representative finite element models were created in order to determine the areas of localized stress concentrations that occur in the bifurcation. The artery is assumed isotropic and is mechanically loaded with an incremental pressure of 40 mmHg. A highly localized stress concentration of approximately 9 to 14 times the proximal circumferential wall stress occurs at the point of bifurcation. A lower stress concentration of approximately 3 to 4 times the proximal circumferential stress occurs over a large area of the sinus bulb. Acknowledging that these two regions of the carotid bifurcation are highly susceptible to atherosclerotic lesions, it appears possible that a correlation between wall stress and atherosclerosis may exist.


Subject(s)
Arteriosclerosis/etiology , Blood Pressure , Carotid Artery Diseases/etiology , Carotid Artery, Common/physiology , Hemorheology , Angiography , Arteriosclerosis/pathology , Calcinosis/pathology , Carotid Artery Diseases/pathology , Carotid Artery, Common/anatomy & histology , Carotid Artery, External/anatomy & histology , Carotid Artery, External/physiology , Carotid Artery, Internal/anatomy & histology , Carotid Artery, Internal/physiology , Disease Susceptibility , Endothelium, Vascular/pathology , Foam Cells/pathology , Humans , Magnetic Resonance Imaging , Models, Biological , Photography , Replica Techniques , Stress, Mechanical , Tunica Intima/pathology
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