ABSTRACT
AIM: to compare the prevalence of Pylori infection in patients with primary open angle glaucoma (POAG) and control group with cataract. METHODS: This is a prospective case-control study. The participants were organized in two groups. First group (case) consisted of 35 patients with POAG and second group consisted of 35 age matched participants with cataract whose optic disk could be evaluated. Serum levels of anti H. pylori IgG antibody were evaluated with the method of ELISA. RESULTS: The seroprevalence of Pylori infection was 89.1 % (33 of 37) in patients with POAG and 59.5 % (25 of 42) in the control group. The difference was significant (P=0.008). The odds ratio for association between Pylori and POAG was 5.69 and the range of 95% confidence interval was from 1.58 to 20.50. CONCLUSION: This study suggests that Helicobacter Pylori infection might be associated with primary open angle glaucoma.
Subject(s)
Glaucoma, Open-Angle/epidemiology , Helicobacter Infections/epidemiology , Adult , Aged , Aged, 80 and over , Antibodies, Bacterial , Case-Control Studies , Enzyme-Linked Immunosorbent Assay , Female , Helicobacter pylori/immunology , Humans , Iran/epidemiology , Male , Middle Aged , Prevalence , Prospective StudiesABSTRACT
There was proposed an expert system for conduction of differential diagnosis of surgical diseases, stimulating the mathematic models creation, the filling up of tables of the features values of all diagnostic hypothesis possible with subsequent staged exception of the least adequate of them. The expert diagnostic system proposed may be applied in clinical practice and pedagogic process while teaching of students.
