ABSTRACT
No disponible
Subject(s)
Humans , Aortic Valve Stenosis/surgery , Transcatheter Aortic Valve Replacement/trends , Heart Valve Prosthesis Implantation/methods , Spain/epidemiology , Treatment OutcomeABSTRACT
Transcatheter aortic valve implantation (TAVI) is associated with various complications, usually related to valve positioning or prosthesis delivery. We report the rare complication of an iatrogenic ventricular septal defect, secondary to aortic annulus disruption after TAVI-transfemoral procedure, generating a significant left-to-right shunt and cardiac failure. Open surgical procedures under cardiopulmonary bypass remain the best option for this lethal complication.
Subject(s)
Aortic Valve Stenosis/surgery , Aortic Valve/surgery , Cardiac Catheterization/adverse effects , Cardiac Catheterization/methods , Heart Septum/injuries , Heart Valve Prosthesis Implantation/adverse effects , Heart Valve Prosthesis Implantation/methods , Iatrogenic Disease , Perioperative Care , Aged , Aortic Valve Stenosis/diagnostic imaging , Echocardiography , Female , Heart Failure/etiology , Humans , Postoperative Complications/etiology , Rupture/etiology , Severity of Illness IndexABSTRACT
We report the use of tigecycline, firstly with colistin and finally alone, in a patient with a persistent breakthrough bacteremia due to a Klebsiella pneumoniae isolate harboring a metallo-beta-lactamase (VIM-1) and an extended-spectrum beta-lactamase (SHV-12). Time-kill studies demonstrated that the combination of both compounds was synergistic along the first 12 h, suppressing the regrowth observed after 3 to 6 h when colistin was tested alone.
