1.
Org Lett
; 24(29): 5372-5375, 2022 07 29.
Article
in English
| MEDLINE
| ID: mdl-35848577
ABSTRACT
An efficient and metal-free strategy for the synthesis of spiro-fused indanolactones/lactams has been developed for the reaction of arynes with α-chloroacetyl lactones/lactams. This strategy provides access to spiroindanone derivatives via aryne insertion/spirocyclization.