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1.
Math Biosci Eng ; 21(4): 5712-5734, 2024 Apr 24.
Article in English | MEDLINE | ID: mdl-38872555

ABSTRACT

This research introduces a novel dual-pathway convolutional neural network (DP-CNN) architecture tailored for robust performance in Log-Mel spectrogram image analysis derived from raw multichannel electromyography signals. The primary objective is to assess the effectiveness of the proposed DP-CNN architecture across three datasets (NinaPro DB1, DB2, and DB3), encompassing both able-bodied and amputee subjects. Performance metrics, including accuracy, precision, recall, and F1-score, are employed for comprehensive evaluation. The DP-CNN demonstrates notable mean accuracies of 94.93 ± 1.71% and 94.00 ± 3.65% on NinaPro DB1 and DB2 for healthy subjects, respectively. Additionally, it achieves a robust mean classification accuracy of 85.36 ± 0.82% on amputee subjects in DB3, affirming its efficacy. Comparative analysis with previous methodologies on the same datasets reveals substantial improvements of 28.33%, 26.92%, and 39.09% over the baseline for DB1, DB2, and DB3, respectively. The DP-CNN's superior performance extends to comparisons with transfer learning models for image classification, reaffirming its efficacy. Across diverse datasets involving both able-bodied and amputee subjects, the DP-CNN exhibits enhanced capabilities, holding promise for advancing myoelectric control.


Subject(s)
Algorithms , Amputees , Electromyography , Gestures , Neural Networks, Computer , Signal Processing, Computer-Assisted , Upper Extremity , Humans , Electromyography/methods , Upper Extremity/physiology , Male , Adult , Female , Young Adult , Middle Aged , Reproducibility of Results
2.
Heliyon ; 10(7): e28967, 2024 Apr 15.
Article in English | MEDLINE | ID: mdl-38601589

ABSTRACT

Plant diseases annually cause damage and loss of much of the crop, if not its complete destruction, and this constitutes a significant challenge for farm owners, governments, and consumers alike. Therefore, identifying and classifying diseases at an early stage is very important in order to sustain local and global food security. In this research, we designed a new method to identify plant diseases by combining transfer learning and Gravitational Search Algorithm (GSA). Two state-of-the-art pretrained models have been adopted for extracting features in this study, which are MobileNetV2 and ResNe50V2. Multilayer feature extraction is applied in this study to ensure representations of plant leaves from different levels of abstraction for precise classification. These features are then concatenated and passed to GSA for optimizing them. Finally, optimized features are passed to Multinomial Logistic Regression (MLR) for final classification. This integration is essential for categorizing 18 different types of infected and healthy leaf samples. The performance of our approach is strengthened by a comparative analysis that incorporates features optimized by the Genetic Algorithm (GA). Additionally, the MLR algorithm is contrasted with K-Nearest Neighbors (KNN). The empirical findings indicate that our model, which has been refined using GSA, achieves very high levels of precision. Specifically, the average precision for MLR is 99.2%, while for KNN it is 98.6%. The resulting results significantly exceed those achieved with GA-optimized features, thereby highlighting the superiority of our suggested strategy. One important result of our study is that we were able to decrease the number of features by more than 50%. This reduction greatly reduces the processing requirements without sacrificing the quality of the diagnosis. This work presents a robust and efficient approach to the early detection of plant diseases. The work demonstrates the utilization of sophisticated computational methods in agriculture, enabling the development of novel data-driven strategies for plant health management, therefore enhancing worldwide food security.

3.
Front Med (Lausanne) ; 11: 1310137, 2024.
Article in English | MEDLINE | ID: mdl-38357646

ABSTRACT

Quality of life is greatly affected by chronic wounds. It requires more intensive care than acute wounds. Schedule follow-up appointments with their doctor to track healing. Good wound treatment promotes healing and fewer problems. Wound care requires precise and reliable wound measurement to optimize patient treatment and outcomes according to evidence-based best practices. Images are used to objectively assess wound state by quantifying key healing parameters. Nevertheless, the robust segmentation of wound images is complex because of the high diversity of wound types and imaging conditions. This study proposes and evaluates a novel hybrid model developed for wound segmentation in medical images. The model combines advanced deep learning techniques with traditional image processing methods to improve the accuracy and reliability of wound segmentation. The main objective is to overcome the limitations of existing segmentation methods (UNet) by leveraging the combined advantages of both paradigms. In our investigation, we introduced a hybrid model architecture, wherein a ResNet34 is utilized as the encoder, and a UNet is employed as the decoder. The combination of ResNet34's deep representation learning and UNet's efficient feature extraction yields notable benefits. The architectural design successfully integrated high-level and low-level features, enabling the generation of segmentation maps with high precision and accuracy. Following the implementation of our model to the actual data, we were able to determine the following values for the Intersection over Union (IOU), Dice score, and accuracy: 0.973, 0.986, and 0.9736, respectively. According to the achieved results, the proposed method is more precise and accurate than the current state-of-the-art.

4.
Article in English | MEDLINE | ID: mdl-38055360

ABSTRACT

The Internet of Things (IoT) is capable of controlling the healthcare monitoring system for remote-based patients. Epilepsy, a chronic brain syndrome characterized by recurrent, unpredictable attacks, affects individuals of all ages. IoT-based seizure monitoring can greatly enhance seizure patients' quality of life. IoT device acquires patient data and transmits it to a computer program so that doctors can examine it. Currently, doctors invest significant manual effort in inspecting Electroencephalograph (EEG) signals to identify seizure activity. However, EEG-based seizure detection algorithms face challenges in real-world scenarios due to non-stationary EEG data and variable seizure patterns among patients and recording sessions. Therefore, a sophisticated computer-based approach is necessary to analyze complex EEG records. In this work, the authors proposed a hybrid approach by combining traditional convolution neural (CN) and recurrent neural networks (RNN) along with an attention mechanism for the automatic recognition of epileptic seizures through EEG signal analysis. This attention mechanism focuses on significant subsets of EEG data for class recognition, resulting in improved model performance. The proposed methods are evaluated using a publicly available UCI epileptic seizure recognition dataset, which consists of five classes: four normal conditions and one abnormal seizure condition. Experimental results demonstrate that the suggested approach achieves an overall accuracy of 97.05% for the five-class EEG recognition data, with an accuracy of 99.52% for binary classification distinguishing seizure cases from normal instances. Furthermore, the proposed intelligent seizure recognition model is compatible with an IoMT (Internet of Medical Things) cloud-based smart healthcare framework.

5.
Diagnostics (Basel) ; 13(23)2023 Nov 21.
Article in English | MEDLINE | ID: mdl-38066735

ABSTRACT

BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating illness with a significant global prevalence, affecting over 65 million individuals. It affects various systems, including the immune, neurological, gastrointestinal, and circulatory systems. Studies have shown abnormalities in immune cell types, increased inflammatory cytokines, and brain abnormalities. Further research is needed to identify consistent biomarkers and develop targeted therapies. This study uses explainable artificial intelligence and machine learning techniques to identify discriminative metabolites for ME/CFS. MATERIAL AND METHODS: The model investigates a metabolomics dataset of CFS patients and healthy controls, including 26 healthy controls and 26 ME/CFS patients aged 22-72. The dataset encapsulated 768 metabolites into nine metabolic super-pathways: amino acids, carbohydrates, cofactors, vitamins, energy, lipids, nucleotides, peptides, and xenobiotics. Random forest methods together with other classifiers were applied to the data to classify individuals as ME/CFS patients and healthy individuals. The classification learning algorithms' performance in the validation step was evaluated using a variety of methods, including the traditional hold-out validation method, as well as the more modern cross-validation and bootstrap methods. Explainable artificial intelligence approaches were applied to clinically explain the optimum model's prediction decisions. RESULTS: The metabolomics of C-glycosyltryptophan, oleoylcholine, cortisone, and 3-hydroxydecanoate were determined to be crucial for ME/CFS diagnosis. The random forest model outperformed the other classifiers in ME/CFS prediction using the 1000-iteration bootstrapping method, achieving 98% accuracy, precision, recall, F1 score, 0.01 Brier score, and 99% AUC. According to the obtained results, the bootstrap validation approach demonstrated the highest classification outcomes. CONCLUSION: The proposed model accurately classifies ME/CFS patients based on the selected biomarker candidate metabolites. It offers a clear interpretation of risk estimation for ME/CFS, aiding physicians in comprehending the significance of key metabolomic features within the model.

6.
BMC Bioinformatics ; 24(1): 372, 2023 Oct 02.
Article in English | MEDLINE | ID: mdl-37784049

ABSTRACT

The rising risk of diabetes, particularly in emerging countries, highlights the importance of early detection. Manual prediction can be a challenging task, leading to the need for automatic approaches. The major challenge with biomedical datasets is data scarcity. Biomedical data is often difficult to obtain in large quantities, which can limit the ability to train deep learning models effectively. Biomedical data can be noisy and inconsistent, which can make it difficult to train accurate models. To overcome the above-mentioned challenges, this work presents a new framework for data modeling that is based on correlation measures between features and can be used to process data effectively for predicting diabetes. The standard, publicly available Pima Indians Medical Diabetes (PIMA) dataset is utilized to verify the effectiveness of the proposed techniques. Experiments using the PIMA dataset showed that the proposed data modeling method improved the accuracy of machine learning models by an average of 9%, with deep convolutional neural network models achieving an accuracy of 96.13%. Overall, this study demonstrates the effectiveness of the proposed strategy in the early and reliable prediction of diabetes.


Subject(s)
Deep Learning , Diabetes Mellitus , Humans , Potassium Iodide , Neural Networks, Computer , Machine Learning , Diabetes Mellitus/diagnosis
7.
Comput Biol Med ; 165: 107389, 2023 10.
Article in English | MEDLINE | ID: mdl-37678138

ABSTRACT

This paper introduces a new bio-inspired optimization algorithm named the Liver Cancer Algorithm (LCA), which mimics the liver tumor growth and takeover process. It uses an evolutionary search approach that simulates the behavior of liver tumors when taking over the liver organ. The tumor's ability to replicate and spread to other organs inspires the algorithm. LCA algorithm is developed using genetic operators and a Random Opposition-Based Learning (ROBL) strategy to efficiently balance local and global searches and explore the search space. The algorithm's efficiency is tested on the IEEE Congress of Evolutionary Computation in 2020 (CEC'2020) benchmark functions and compared to seven widely used metaheuristic algorithms, including Genetic Algorithm (GA), particle swarm optimization (PSO), Differential Evolution (DE), Adaptive Guided Differential Evolution Algorithm (AGDE), Improved Multi-Operator Differential Evolution (IMODE), Harris Hawks Optimization (HHO), Runge-Kutta Optimization Algorithm (RUN), weIghted meaN oF vectOrs (INFO), and Coronavirus Herd Immunity Optimizer (CHIO). The statistical results of the convergence curve, boxplot, parameter space, and qualitative metrics show that the LCA algorithm performs competitively compared to well-known algorithms. Moreover, the versatility of the LCA algorithm extends beyond mathematical benchmark problems. It was also successfully applied to tackle the feature selection problem and optimize the support vector machine for various biomedical data classifications, resulting in the creation of the LCA-SVM model. The LCA-SVM model was evaluated in a total of twelve datasets, among which the MonoAmine Oxidase (MAO) dataset stood out, showing the highest performance compared to the other datasets. In particular, the LCA-SVM model achieved an impressive accuracy of 98.704% on the MAO dataset. This outstanding result demonstrates the efficacy and potential of the LCA-SVM approach in handling complex datasets and producing highly accurate predictions. The experimental results indicate that the LCA algorithm surpasses other methods to solve mathematical benchmark problems and feature selection.


Subject(s)
Liver Neoplasms , Humans , Algorithms , Benchmarking , Monoamine Oxidase
8.
Comput Biol Med ; 164: 107237, 2023 09.
Article in English | MEDLINE | ID: mdl-37467535

ABSTRACT

Medical datasets are primarily made up of numerous pointless and redundant elements in a collection of patient records. None of these characteristics are necessary for a medical decision-making process. Conversely, a large amount of data leads to increased dimensionality and decreased classifier performance in terms of machine learning. Numerous approaches have recently been put out to address this issue, and the results indicate that feature selection can be a successful remedy. To meet the various needs of input patterns, medical diagnostic tasks typically involve learning a suitable categorization model. The k-Nearest Neighbors algorithm (kNN) classifier's classification performance is typically decreased by the input variables' abundance of irrelevant features. To simplify the kNN classifier, essential attributes of the input variables have been searched using the feature selection approach. This paper presents the Coati Optimization Algorithm (DCOA) in a dynamic form as a feature selection technique where each iteration of the optimization process involves the introduction of a different feature. We enhance the exploration and exploitation capability of DCOA by employing dynamic opposing candidate solutions. The most impressive feature of DCOA is that it does not require any preparatory parameter fine-tuning to the most popular metaheuristic algorithms. The CEC'22 test suite and nine medical datasets with various dimension sizes were used to evaluate the performance of the original COA and the proposed dynamic version. The statistical results were validated using the Bonferroni-Dunn test and Kendall's W test and showed the superiority of DCOA over seven well-known metaheuristic algorithms with an overall accuracy of 89.7%, a feature selection of 24%, a sensitivity of 93.35% a specificity of 96.81%, and a precision of 93.90%.


Subject(s)
Procyonidae , Humans , Animals , Algorithms , Machine Learning
9.
Life (Basel) ; 13(6)2023 May 29.
Article in English | MEDLINE | ID: mdl-37374060

ABSTRACT

The domestication of animals and the cultivation of crops have been essential to human development throughout history, with the agricultural sector playing a pivotal role. Insufficient nutrition often leads to plant diseases, such as those affecting rice crops, resulting in yield losses of 20-40% of total production. These losses carry significant global economic consequences. Timely disease diagnosis is critical for implementing effective treatments and mitigating financial losses. However, despite technological advancements, rice disease diagnosis primarily depends on manual methods. In this study, we present a novel self-attention network (SANET) based on the ResNet50 architecture, incorporating a kernel attention mechanism for accurate AI-assisted rice disease classification. We employ attention modules to extract contextual dependencies within images, focusing on essential features for disease identification. Using a publicly available rice disease dataset comprising four classes (three disease types and healthy leaves), we conducted cross-validated classification experiments to evaluate our proposed model. The results reveal that the attention-based mechanism effectively guides the convolutional neural network (CNN) in learning valuable features, resulting in accurate image classification and reduced performance variation compared to state-of-the-art methods. Our SANET model achieved a test set accuracy of 98.71%, surpassing that of current leading models. These findings highlight the potential for widespread AI adoption in agricultural disease diagnosis and management, ultimately enhancing efficiency and effectiveness within the sector.

10.
Diagnostics (Basel) ; 13(9)2023 May 03.
Article in English | MEDLINE | ID: mdl-37175012

ABSTRACT

It is crucial to accurately categorize cancers using microarray data. Researchers have employed a variety of computational intelligence approaches to analyze gene expression data. It is believed that the most difficult part of the problem of cancer diagnosis is determining which genes are informative. Therefore, selecting genes to study as a starting point for cancer classification is common practice. We offer a novel approach that combines the Runge Kutta optimizer (RUN) with a support vector machine (SVM) as the classifier to select the significant genes in the detection of cancer tissues. As a means of dealing with the high dimensionality that characterizes microarray datasets, the preprocessing stage of the ReliefF method is implemented. The proposed RUN-SVM approach is tested on binary-class microarray datasets (Breast2 and Prostate) and multi-class microarray datasets in order to assess its efficacy (i.e., Brain Tumor1, Brain Tumor2, Breast3, and Lung Cancer). Based on the experimental results obtained from analyzing six different cancer gene expression datasets, the proposed RUN-SVM approach was found to statistically beat the other competing algorithms due to its innovative search technique.

11.
Comput Biol Med ; 160: 106966, 2023 06.
Article in English | MEDLINE | ID: mdl-37141655

ABSTRACT

One of the worst diseases is a brain tumor, which is defined by abnormal development of synapses in the brain. Early detection of brain tumors is essential for improving prognosis, and classifying tumors is a vital step in the disease's treatment. Different classification strategies using deep learning have been presented for the diagnosis of brain tumors. However, several challenges exist, such as the need for a competent specialist in classifying brain cancers by deep learning models and the problem of building the most precise deep learning model for categorizing brain tumors. We propose an evolved and highly efficient model based on deep learning and improved metaheuristic algorithms to address these challenges. Specifically, we develop an optimized residual learning architecture for classifying multiple brain tumors and propose an improved variant of the Hunger Games Search algorithm (I-HGS) based on combining two enhancing strategies: Local Escaping Operator (LEO) and Brownian motion. These two strategies balance solution diversity and convergence speed, boosting the optimization performance and staying away from the local optima. First, we have evaluated the I-HGS algorithm on the IEEE Congress on Evolutionary Computation held in 2020 (CEC'2020) test functions, demonstrating that I-HGS outperformed the basic HGS and other popular algorithms regarding statistical convergence, and various measures. The suggested model is then applied to the optimization of the hyperparameters of the Residual Network 50 (ResNet50) model (I-HGS-ResNet50) for brain cancer identification, proving its overall efficacy. We utilize several publicly available, gold-standard datasets of brain MRI images. The proposed I-HGS-ResNet50 model is compared with other existing studies as well as with other deep learning architectures, including Visual Geometry Group 16-layer (VGG16), MobileNet, and Densely Connected Convolutional Network 201 (DenseNet201). The experiments demonstrated that the proposed I-HGS-ResNet50 model surpasses the previous studies and other well-known deep learning models. I-HGS-ResNet50 acquired an accuracy of 99.89%, 99.72%, and 99.88% for the three datasets. These results efficiently prove the potential of the proposed I-HGS-ResNet50 model for accurate brain tumor classification.


Subject(s)
Brain Neoplasms , Deep Learning , Humans , Algorithms , Brain/diagnostic imaging , Brain Neoplasms/diagnostic imaging
12.
Healthcare (Basel) ; 10(12)2022 Nov 22.
Article in English | MEDLINE | ID: mdl-36553864

ABSTRACT

Brain tumors (BTs) are an uncommon but fatal kind of cancer. Therefore, the development of computer-aided diagnosis (CAD) systems for classifying brain tumors in magnetic resonance imaging (MRI) has been the subject of many research papers so far. However, research in this sector is still in its early stage. The ultimate goal of this research is to develop a lightweight effective implementation of the U-Net deep network for use in performing exact real-time segmentation. Moreover, a simplified deep convolutional neural network (DCNN) architecture for the BT classification is presented for automatic feature extraction and classification of the segmented regions of interest (ROIs). Five convolutional layers, rectified linear unit, normalization, and max-pooling layers make up the DCNN's proposed simplified architecture. The introduced method was verified on multimodal brain tumor segmentation (BRATS 2015) datasets. Our experimental results on BRATS 2015 acquired Dice similarity coefficient (DSC) scores, sensitivity, and classification accuracy of 88.8%, 89.4%, and 88.6% for high-grade gliomas. When it comes to segmenting BRATS 2015 BT images, the performance of our proposed CAD framework is on par with existing state-of-the-art methods. However, the accuracy achieved in this study for the classification of BT images has improved upon the accuracy reported in prior studies. Image classification accuracy for BRATS 2015 BT has been improved from 88% to 88.6%.

13.
Life (Basel) ; 12(12)2022 Nov 22.
Article in English | MEDLINE | ID: mdl-36556313

ABSTRACT

Epilepsy is a common neurological condition. The effects of epilepsy are not restricted to seizures alone. They comprise a wide spectrum of problems that might impair and reduce quality of life. Even with medication, 30% of epilepsy patients still have recurring seizures. An epileptic seizure is caused by significant neuronal electrical activity, which affects brain activity. EEG shows these changes as high-amplitude spiky and sluggish waves. Recognizing seizures on an electroencephalogram (EEG) manually by a professional neurologist is a time-consuming and labor-intensive process, hence an efficient automated approach is necessary for the identification of epileptic seizure. One technique to increase the speed and accuracy with which a diagnosis of epileptic seizures could be made is by utilizing computer-aided diagnosis systems that are built on deep neural networks, or DNN. This study introduces a fusion of recurrent neural networks (RNNs) and bi-directional long short-term memories (BiLSTMs) for automatic epileptic seizure identification via EEG signal processing in order to tackle the aforementioned informational challenges. An electroencephalogram's (EEG) raw data were first normalized after undergoing pre-processing. A RNN model was fed the normalized EEG sequence data and trained to accurately extract features from the data. Afterwards, the features were passed to the BiLSTM layers for processing so that further temporal information could be retrieved. In addition, the proposed RNN-BiLSTM model was tested in an experimental setting using the freely accessible UCI epileptic seizure dataset. Experimental findings of the suggested model have achieved avg values of 98.90%, 98.50%, 98. 20%, and 98.60%, respectively, for accuracy, sensitivity, precision, and specificity. To further verify the new model's efficacy, it is compared to other models, such as the RNN-LSTM and the RNN-GRU learning models, and is shown to have improved the same metrics by 1.8%, 1.69%, 1.95%, and 2.2% on using 5-fold. Additionally, the proposed method was compared to state-of-the-art approaches and proved to be a more accurate categorization of such techniques.

14.
Biomedicines ; 10(11)2022 Nov 18.
Article in English | MEDLINE | ID: mdl-36428538

ABSTRACT

Breast cancer, which attacks the glandular epithelium of the breast, is the second most common kind of cancer in women after lung cancer, and it affects a significant number of people worldwide. Based on the advantages of Residual Convolutional Network and the Transformer Encoder with Multiple Layer Perceptron (MLP), this study proposes a novel hybrid deep learning Computer-Aided Diagnosis (CAD) system for breast lesions. While the backbone residual deep learning network is employed to create the deep features, the transformer is utilized to classify breast cancer according to the self-attention mechanism. The proposed CAD system has the capability to recognize breast cancer in two scenarios: Scenario A (Binary classification) and Scenario B (Multi-classification). Data collection and preprocessing, patch image creation and splitting, and artificial intelligence-based breast lesion identification are all components of the execution framework that are applied consistently across both cases. The effectiveness of the proposed AI model is compared against three separate deep learning models: a custom CNN, the VGG16, and the ResNet50. Two datasets, CBIS-DDSM and DDSM, are utilized to construct and test the proposed CAD system. Five-fold cross validation of the test data is used to evaluate the accuracy of the performance results. The suggested hybrid CAD system achieves encouraging evaluation results, with overall accuracies of 100% and 95.80% for binary and multiclass prediction challenges, respectively. The experimental results reveal that the proposed hybrid AI model could identify benign and malignant breast tissues significantly, which is important for radiologists to recommend further investigation of abnormal mammograms and provide the optimal treatment plan.

15.
Diagnostics (Basel) ; 12(11)2022 Nov 16.
Article in English | MEDLINE | ID: mdl-36428875

ABSTRACT

Blood cells carry important information that can be used to represent a person's current state of health. The identification of different types of blood cells in a timely and precise manner is essential to cutting the infection risks that people face on a daily basis. The BCNet is an artificial intelligence (AI)-based deep learning (DL) framework that was proposed based on the capability of transfer learning with a convolutional neural network to rapidly and automatically identify the blood cells in an eight-class identification scenario: Basophil, Eosinophil, Erythroblast, Immature Granulocytes, Lymphocyte, Monocyte, Neutrophil, and Platelet. For the purpose of establishing the dependability and viability of BCNet, exhaustive experiments consisting of five-fold cross-validation tests are carried out. Using the transfer learning strategy, we conducted in-depth comprehensive experiments on the proposed BCNet's architecture and test it with three optimizers of ADAM, RMSprop (RMSP), and stochastic gradient descent (SGD). Meanwhile, the performance of the proposed BCNet is directly compared using the same dataset with the state-of-the-art deep learning models of DensNet, ResNet, Inception, and MobileNet. When employing the different optimizers, the BCNet framework demonstrated better classification performance with ADAM and RMSP optimizers. The best evaluation performance was achieved using the RMSP optimizer in terms of 98.51% accuracy and 96.24% F1-score. Compared with the baseline model, the BCNet clearly improved the prediction accuracy performance 1.94%, 3.33%, and 1.65% using the optimizers of ADAM, RMSP, and SGD, respectively. The proposed BCNet model outperformed the AI models of DenseNet, ResNet, Inception, and MobileNet in terms of the testing time of a single blood cell image by 10.98, 4.26, 2.03, and 0.21 msec. In comparison to the most recent deep learning models, the BCNet model could be able to generate encouraging outcomes. It is essential for the advancement of healthcare facilities to have such a recognition rate improving the detection performance of the blood cells.

16.
Diagnostics (Basel) ; 12(10)2022 Oct 20.
Article in English | MEDLINE | ID: mdl-36292230

ABSTRACT

Brain tumors (BTs) are deadly diseases that can strike people of every age, all over the world. Every year, thousands of people die of brain tumors. Brain-related diagnoses require caution, and even the smallest error in diagnosis can have negative repercussions. Medical errors in brain tumor diagnosis are common and frequently result in higher patient mortality rates. Magnetic resonance imaging (MRI) is widely used for tumor evaluation and detection. However, MRI generates large amounts of data, making manual segmentation difficult and laborious work, limiting the use of accurate measurements in clinical practice. As a result, automated and dependable segmentation methods are required. Automatic segmentation and early detection of brain tumors are difficult tasks in computer vision due to their high spatial and structural variability. Therefore, early diagnosis or detection and treatment are critical. Various traditional Machine learning (ML) techniques have been used to detect various types of brain tumors. The main issue with these models is that the features were manually extracted. To address the aforementioned insightful issues, this paper presents a hybrid deep transfer learning (GN-AlexNet) model of BT tri-classification (pituitary, meningioma, and glioma). The proposed model combines GoogleNet architecture with the AlexNet model by removing the five layers of GoogleNet and adding ten layers of the AlexNet model, which extracts features and classifies them automatically. On the same CE-MRI dataset, the proposed model was compared to transfer learning techniques (VGG-16, AlexNet, SqeezNet, ResNet, and MobileNet-V2) and ML/DL. The proposed model outperformed the current methods in terms of accuracy and sensitivity (accuracy of 99.51% and sensitivity of 98.90%).

17.
Healthcare (Basel) ; 10(8)2022 Aug 22.
Article in English | MEDLINE | ID: mdl-36011249

ABSTRACT

Home healthcare agencies (HHCAs) provide clinical care and rehabilitation services to patients in their own homes. The organization's rules regulate several connected practitioners, doctors, and licensed skilled nurses. Frequently, it monitors a physician or licensed nurse for the facilities and keeps track of the health histories of all clients. HHCAs' quality of care is evaluated using Medicare's star ratings for in-home healthcare agencies. The advent of technology has extensively evolved our living style. Online businesses' ratings and reviews are the best representatives of organizations' trust, services, quality, and ethics. Using data mining techniques to analyze HHCAs' data can help to develop an effective framework for evaluating the finest home healthcare facilities. As a result, we developed an automated predictive framework for obtaining knowledge from patients' feedback using a combination of statistical and machine learning techniques. HHCAs' data contain twelve performance characteristics that we are the first to analyze and depict. After adequate pattern recognition, we applied binary and multi-class approaches on similar data with variations in the target class. Four prominent machine learning models were considered: SVM, Decision Tree, Random Forest, and Deep Neural Networks. In the binary class, the Deep Neural Network model presented promising performance with an accuracy of 97.37%. However, in the case of multiple class, the random forest model showed a significant outcome with an accuracy of 91.87%. Additionally, variable significance is derived from investigating each attribute's importance in predictive model building. The implications of this study can support various stakeholders, including public agencies, quality measurement, healthcare inspectors, and HHCAs, to boost their performance. Thus, the proposed framework is not only useful for putting valuable insights into action, but it can also help with decision-making.

18.
Sensors (Basel) ; 22(15)2022 Jul 24.
Article in English | MEDLINE | ID: mdl-35898023

ABSTRACT

Acute lymphoblastic leukemia (ALL) is a deadly cancer characterized by aberrant accumulation of immature lymphocytes in the blood or bone marrow. Effective treatment of ALL is strongly associated with the early diagnosis of the disease. Current practice for initial ALL diagnosis is performed through manual evaluation of stained blood smear microscopy images, which is a time-consuming and error-prone process. Deep learning-based human-centric biomedical diagnosis has recently emerged as a powerful tool for assisting physicians in making medical decisions. Therefore, numerous computer-aided diagnostic systems have been developed to autonomously identify ALL in blood images. In this study, a new Bayesian-based optimized convolutional neural network (CNN) is introduced for the detection of ALL in microscopic smear images. To promote classification performance, the architecture of the proposed CNN and its hyperparameters are customized to input data through the Bayesian optimization approach. The Bayesian optimization technique adopts an informed iterative procedure to search the hyperparameter space for the optimal set of network hyperparameters that minimizes an objective error function. The proposed CNN is trained and validated using a hybrid dataset which is formed by integrating two public ALL datasets. Data augmentation has been adopted to further supplement the hybrid image set to boost classification performance. The Bayesian search-derived optimal CNN model recorded an improved performance of image-based ALL classification on test set. The findings of this study reveal the superiority of the proposed Bayesian-optimized CNN over other optimized deep learning ALL classification models.


Subject(s)
Neural Networks, Computer , Precursor Cell Lymphoblastic Leukemia-Lymphoma , Bayes Theorem , Humans , Microscopy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
19.
Sensors (Basel) ; 22(13)2022 Jun 30.
Article in English | MEDLINE | ID: mdl-35808433

ABSTRACT

One of the most promising research areas in the healthcare industry and the scientific community is focusing on the AI-based applications for real medical challenges such as the building of computer-aided diagnosis (CAD) systems for breast cancer. Transfer learning is one of the recent emerging AI-based techniques that allow rapid learning progress and improve medical imaging diagnosis performance. Although deep learning classification for breast cancer has been widely covered, certain obstacles still remain to investigate the independency among the extracted high-level deep features. This work tackles two challenges that still exist when designing effective CAD systems for breast lesion classification from mammograms. The first challenge is to enrich the input information of the deep learning models by generating pseudo-colored images instead of only using the input original grayscale images. To achieve this goal two different image preprocessing techniques are parallel used: contrast-limited adaptive histogram equalization (CLAHE) and Pixel-wise intensity adjustment. The original image is preserved in the first channel, while the other two channels receive the processed images, respectively. The generated three-channel pseudo-colored images are fed directly into the input layer of the backbone CNNs to generate more powerful high-level deep features. The second challenge is to overcome the multicollinearity problem that occurs among the high correlated deep features generated from deep learning models. A new hybrid processing technique based on Logistic Regression (LR) as well as Principal Components Analysis (PCA) is presented and called LR-PCA. Such a process helps to select the significant principal components (PCs) to further use them for the classification purpose. The proposed CAD system has been examined using two different public benchmark datasets which are INbreast and mini-MAIS. The proposed CAD system could achieve the highest performance accuracies of 98.60% and 98.80% using INbreast and mini-MAIS datasets, respectively. Such a CAD system seems to be useful and reliable for breast cancer diagnosis.


Subject(s)
Breast Neoplasms , Neural Networks, Computer , Breast Neoplasms/diagnostic imaging , Female , Humans , Logistic Models , Machine Learning , Mammography/methods
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