ABSTRACT
BACKGROUND: Breast cancer is one of the most common cancers amongst women in developed and developing countries. It is associated with the highest mortality rate in low to average-income countries. Breast cancer investigation amongst Iranian women reveals that the number of its incidence is yet the highest in all cancer types. Despite recent longer survival time of women with breast cancer, most of the patients suffer from long term physical and mental distress due to combined treatments. Exercise interventions are among new approaches to promote the better quality of life of the patients, which has only recently been considered by researchers. This study aimed to investigate the effect of exercise intervention on the quality of life of breast cancer survivors. MATERIALS AND METHODS: This is a clinical trial conducted on 80 women with I-III breast cancer, at 18-55 years of age mostly two years after the completion of their treatment in Seyed al Shohada hospital in Isfahan. They were randomly divided into two groups of study and control. Exercise intervention went on for 8 weeks in the study group (three sessions a week, 60 minutes). Quality of life in both groups was measured a day before, and at the end of the eight weeks period by the instrument of the National Medical Center and Beckman Research Institute. The data were analyzed by descriptive and inferential statistical tests of X2, t-test and Mac Hammer test. FINDINGS: Results showed that there was no significant difference in the mean score of the physical dimension of quality of life in the study group before and after intervention while the score of physical health was significantly better in the control group (p < 0.00).The mean score of mental dimension had increased in the study group, while it had decreased in the control group. The mean score of social health showed no significant difference before and after intervention. The mean score of spiritual health had significantly decreased in the control group, while it had significantly increased in the study group (p = 0.004). Generally, the total mean score of the quality of life showed no significant difference before and after intervention. However, the percentage of the quality of life score increased in the study group, but decreased in the control group. CONCLUSIONS: The results of this study showed that exercise interventions can promote a better quality of life for the patients, and increase the total score of quality of life. Although, the total score of quality of life was not significantly different, it was concluded that exercise can promote the quality of life amongst patients with breast cancer.
ABSTRACT
INTRODUCTION: Cancer and its treatments have a significant effect on the Quality of Life (QoL) of people who suffer from cancer. Nursing consultation involving cancer survivors might be beneficial for other patients as they successfully managed and lived with cancer. But controversies still exist in the research findings as how nursing consultation involving cancer survivors might influence other cancer patients' QoL. Therefore, a research study was done to determine the effect of nursing consultation with the presence of cancer survivors on cancer patients' QoL. MATERIALS AND METHODS: The study was a quasi-experimental research using a pre-post test design, which was conducted in Sayyed- AL-Shohada Hospital affiliated to Isfahan University of Medical Sciences, Iran, in 2010. Twenty-two adult patients who suffered from acute leukemia who were receiving chemotherapy were selected. They participated in a nursing consultation group in which cancer survivors were actively engaged. The patients' QoL was assessed before, 1 week, and 1 month after the nursing consultation using the European Organization for Research and Treatment of Cancer Quality of Life Core-30 Version 3 (EORTC QLQ-C30-V3) questionnaire. RESULTS: Comparing QoL mean scores of patients in the symptom, performance, and the general health status scales showed that there was not any significant change in the QoL scores before, 1 week, and 1 month after the consultation. CONCLUSION: It seems that the nursing consultation with the presence of cancer survivors couldn't enhance patients' QoL, although it might prevent worsening the patients' QoL. Cancer has deleterious impacts on patients' QoL and nursing consultation may not improve QoL in a short period of time. It is recommended that the study be conducted with a larger sample, in a longer time and with a case-control design.
ABSTRACT
The association of solid tumors with idiopathic thrombocytopenic purpura (ITP) is rare. However, there have been some case reports indicating an association between breast cancer and ITP. In this article four patients with breast cancer and ITP are mentioned. The diagnosis of breast cancer was based on the results of biopsy or surgical sample. The ITP diagnosis criteria were 1) exclusion of drug induced thrombocytopenia, 2) platelet count less than 140 × 109 /l with normal or increased number of megakaryocytes on bone marrow samples, and 3) absence of splenomegaly. In this case report an association of breast cancer and ITP is shown.
