ABSTRACT
PURPOSE: To study the micro-topography of the abdominal wall of the esophagus and give it a quantitative characterization of tumor pathology of the esophagus. METHODS: The study was performed using morphological methods: 1 anatomical dissection; 2 gistotopographical method with coloring of gistotopogramms with hematoxylin-eosin and Van Gieson; 3 Morphometry of macro and microstructures of the esophagus. Operating studied material from 15 patients who over the tumor lesion was performed resection of the lower third of the esophagus and the upper part of the stomach. Operations were carried out on the basis of the thoracic department of the Orenburg Regional Clinical Oncology Center (ORCOC). RESULTS: This article describes the features of the morphological changes in the abdominal wall of the esophagus at its two forms of tumor lesions: in squamous cell carcinoma and in adenocarcinoma. For adenocarcinoma and squamous cell carcinoma is characterized by a different type of growth, a different degree of sprouting layers of the esophageal wall, different propensity to metastasize within the wall of the esophagus. Submucosa of the esophagus is the main layer in which there are significant changes in neoplastic lesions of the esophagus, both within tumor and in adjacent areas of the esophageal wall. CONCLUSION: The common involvement of submucosa of the abdominal esophagus in the pathological process in its malignant lesions (up to 5 cm in our study) should be considered when determining the upper limit of esophageal resection.
Subject(s)
Adenocarcinoma/pathology , Carcinoma, Squamous Cell/pathology , Esophageal Neoplasms/pathology , Adenocarcinoma/surgery , Carcinoma, Squamous Cell/surgery , Esophageal Neoplasms/surgery , Esophagectomy , Humans , Male , Middle AgedABSTRACT
Experimental study of morphological peculiarities of intestinal wall and common bile duct wall healing using microsurgical sutures under the condition of peritonitis and cholangitis, was performed in 112 dogs. It was shown that the microsurgical suturing of intestinal wall and common bile duct wall affected by the inflammatory process, created the favorable conditions for wound healing. During the recovery period, the thickness of all the layers of the intestinal wall decreased, the disturbances of the normal fibrous structure and the vascular reaction of the submucosa were reduced. Connective tissue capsule was formed around the threads. The structure of the suture zone was not different from that of the neighboring areas of the intestine.
Subject(s)
Gastrointestinal Tract/surgery , Peritonitis/surgery , Sutures , Animals , Dogs , Gastrointestinal Tract/pathology , Humans , Inflammation/pathology , Microsurgery , Peritonitis/pathology , Wound HealingABSTRACT
Histotopographical study of the main and lobar bronchus was performed from 15 corpses of people aged from 23 to 62 who did not die from lung pathology. The peculiarities of histotopography and their possible application in microsurgical operations on bronchus were shown.