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Vestn Ross Akad Med Nauk ; (9): 18-21, 1994.
Article in Russian | MEDLINE | ID: mdl-7532487

ABSTRACT

The paper describes the procedure for producing monoclonal antibodies to human respiratory asyncytial virus using hybridoma technology. Two groups of antibodies were identified in the study of their specific activity. The representatives of the first group preferably reacted with purified virus antigens. Those of the second one binded mostly to unpurified virus antigens from the cultural fluid. The antibodies of these groups appear to be different in their epitope specificity.


Subject(s)
Antigens, Viral/immunology , Hybridomas/virology , Respiratory Syncytial Virus, Human/immunology , Animals , Antibodies, Monoclonal , Cells, Cultured , Humans , Mice , Mice, Inbred BALB C
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