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Bull Exp Biol Med ; 152(5): 624-6, 2012 Mar.
Article in English, Russian | MEDLINE | ID: mdl-22803150

ABSTRACT

The effects of fullerene C(60) nanocomposites on human platelet aggregation induced by ADP, ristocetin, and collagen were studied. The nanocomposite containing fullerene C(60) in polyvinyl pyrrolidone solution did not change platelet aggregation, while fullerene C(60) in crown ether and Twin-80 solutions inhibited ADP-induced platelet aggregation by 20 and 30%, respectively.


Subject(s)
Blood Platelets/drug effects , Fullerenes/pharmacology , Nanocomposites/chemistry , Platelet Aggregation/drug effects , Adenosine Diphosphate/pharmacology , Cells, Cultured , Collagen/pharmacology , Crown Ethers/chemistry , Fullerenes/chemistry , Humans , Platelet Aggregation Inhibitors/pharmacology , Povidone/chemistry , Ristocetin/pharmacology , Surface-Active Agents/chemistry
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