ABSTRACT
OBJECTIVE: To determine the incidence of respiratory function changes on quantified ventilation-perfusion scintigraphy produced by breast cancer radiation therapy and its correlation with irradiated lung volume. MATERIAL AND METHODS: Prospective study on 43 patients with breast cancer who received adjuvant radiotherapy. Quantified ventilation-perfusion scintigraphy was carried out before and after radiotherapy (3 and 9 months). The differences of ventilation and perfusion were calculated subtracting the irradiated lung values from the contralateral lung values, and their correlations with the irradiated lung volume were analyzed. RESULTS: The scintigraphic parameter means of the irradiated lung were significantly lower than those of the contralateral lung, after radiotherapy. The incidence of patients with a total perfusion and ventilation decrease over 10 % was 21 %, except for the three-month ventilation, which was 23 %. The total ventilation difference was significantly correlated with the lung volume, presenting decreases over 10 % for volumes of 100 cm3 or more. All patients remained asymptomatic. CONCLUSIONS: The pulmonary scintigraphy changes derived from the breast cancer radiotherapy produced no clinical symptomatology. Regarding scintigraphy, ventilation decreases when the irradiated lung volume increases, so a follow-up of these patients' pulmonary function should be performed when the lung volume irradiation cannot be lower than 100 cm3.
Subject(s)
Breast Neoplasms/radiotherapy , Lung/diagnostic imaging , Radiation Injuries/diagnostic imaging , Adult , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Breast Neoplasms/therapy , Combined Modality Therapy , Female , Humans , Incidence , Lung/physiopathology , Lung Injury , Lung Volume Measurements , Mastectomy , Middle Aged , Prospective Studies , Radiation Injuries/epidemiology , Radionuclide Imaging , Ventilation-Perfusion RatioABSTRACT
Objetivo: Determinar, mediante gammagrafía de ventilación y perfusión cuantificada, la incidencia de alteraciones en la función respiratoria producidas por la irradiación en el cáncer de mama, y su correlación con el volumen de pulmón irradiado.Material y métodos: Estudio prospectivo de 43 pacientes con cáncer de mama sometidas a radioterapia complementaria. Se practicó gammagrafía pulmonar de ventilación y perfusión cuantificada antes y después de la radioterapia (a los 3 y 9 meses). Las diferencias de perfusión y ventilación se calcularon restando a los valores obtenidos para el pulmón irradiado los valores del pulmón contralateral y se estudió su relación con el volumen pulmonar irradiado.Resultados: Las medias de los parámetros gammagráficos del pulmón irradiado fueron inferiores a las del pulmón contralateral, de forma significativa, después de la radioterapia. La incidencia de pacientes con descenso de perfusión y ventilación global superiores al 10 por ciento fue 21 por ciento, excepto para la ventilación a los 3 meses, que fue 23 por ciento. La diferencia de ventilación global se correlacionó de forma significativa con el volumen pulmonar, apreciándose descensos superiores al 10 por ciento a partir de 100 cm3.Todas las pacientes permanecieron asintomáticas.Conclusiones: Los cambios gammagráficos de ventilación y perfusión derivados de la irradiación pulmonar no produjeron sintomatología clínica alguna. Gammagráficamente, la ventilación desciende con el incremento del volumen pulmonar irradiado, siendo recomendable llevar a cabo un seguimiento de la función pulmonar de estas pacientes cuando no sea factible la irradiación de un volumen de pulmón inferior a 100 cm3. (AU)
Subject(s)
Middle Aged , Adult , Aged , Female , Humans , Ventilation-Perfusion Ratio , Incidence , Prospective Studies , Radiation Injuries , Antineoplastic Combined Chemotherapy Protocols , Combined Modality Therapy , Mastectomy , Lung Volume Measurements , Lung , Breast NeoplasmsABSTRACT
Between the plasma-cell neoplasms the solitary osseous plasmocitoma represents a low percentage of the whole totality. Unlike the multiple myeloma the plasmocytoma is a lesion potencially curable. The diagnose criteria that must fulfil these lesions are detailed. The AA. report a case sitting in the lower jaw. Review of the previous 28 cases communicated in the anglo-saxon literature. Special attention is paid to the radiotherapy on this sickness.
Subject(s)
Mandible/pathology , Mandibular Neoplasms/pathology , Plasmacytoma/pathology , Adult , Aged , Female , Humans , Male , Mandible/radiation effects , Mandible/ultrastructure , Mandibular Neoplasms/radiotherapy , Mandibular Neoplasms/ultrastructure , Middle Aged , Plasmacytoma/radiotherapy , Plasmacytoma/ultrastructure , Radiation DosageABSTRACT
Report of the results of radiotherapy in 12 patients suffering from chemodectomas of the temporal bone. Complete or partial remissions under both clinical and radiological aspects are argued. Discussion on radiotherapy versus surgery of these growths.
