ABSTRACT
The efficacy and prognostic significance of the forced intraarterial injection of medicinal preparations in complex of treatment in patients, suffering chronic ischemia of the lower extremities tissues, was studied. In experimental conditions of the main blood flow blockade the forced intraarterial injection of medicinal preparations have promoted the release of vessels from cellular aggregates and the blood clots; and in the ischemia of degree ÐÐ - ÐÐÐа has determined more pronounced clinical improvement. Appearance of reactive hyperemia of the foot in terms more than 2 min have witnessed the hopelessness of the extremity saving.
Subject(s)
Anesthetics, Local/therapeutic use , Anticoagulants/therapeutic use , Arteriosclerosis Obliterans/therapy , Endarteritis/therapy , Ischemia/therapy , Peripheral Arterial Disease/therapy , Vasodilator Agents/therapeutic use , Adult , Aged , Aged, 80 and over , Animals , Arteriosclerosis Obliterans/pathology , Arteriosclerosis Obliterans/surgery , Cats , Endarteritis/pathology , Endarteritis/surgery , Female , Heparin/therapeutic use , Humans , Hydrostatic Pressure , Injections, Intra-Arterial/methods , Ischemia/pathology , Ischemia/surgery , Lower Extremity/blood supply , Lower Extremity/pathology , Male , Middle Aged , Pentoxifylline/therapeutic use , Peripheral Arterial Disease/pathology , Peripheral Arterial Disease/surgery , Procaine/therapeutic useABSTRACT
The interventions efficacy, conducted on a nervous structures in 198 patients for occlusive diseases of the lower extremities arteries, in 68 of whom a femoral and sciatic nerves blockade were performed together with epidural anesthesia and open alcoholizing of sciatic nerve, was estimated. Efficacy of partial denervation in complex treatment of patients, suffering chronic ischemia of the lower extremities stages II - IlIA, was established, when performance of a direct revascularization is impossible because of a secured functional reserve present.
Subject(s)
Arteriosclerosis Obliterans/therapy , Diabetic Foot/therapy , Lower Extremity/blood supply , Lower Extremity/innervation , Nerve Block/methods , Pain/prevention & control , Adult , Aged , Aged, 80 and over , Arteriosclerosis Obliterans/diagnosis , Chronic Disease , Combined Modality Therapy , Diabetic Foot/diagnosis , Female , Humans , Male , Middle Aged , Severity of Illness Index , Treatment OutcomeSubject(s)
Polymers/therapeutic use , Wound Infection/drug therapy , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle AgedSubject(s)
Appendicitis/epidemiology , Acute Disease , Appendectomy , Appendicitis/surgery , Cohort Studies , Female , Humans , Male , Sex Factors , Ukraine/epidemiologySubject(s)
Intestinal Fistula/surgery , Intestine, Small , Acute Disease , Age Factors , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Intestine, Small/surgery , Time FactorsABSTRACT
The peculiarities of a contact of the sorbent particles of a polysorb for medical purposes with the somatic cells have been studied. The destructive action of the preparation its capability to block the functionally active sites of a cellular membrane were revealed. The recommendations on clinical use of a polysorb have been developed.
Subject(s)
Polymers/pharmacology , Silicon Dioxide/pharmacology , Sorption Detoxification/methods , Wound Healing/drug effects , B-Lymphocytes/drug effects , Erythrocytes/drug effects , Humans , In Vitro Techniques , Rosette Formation , T-Lymphocytes/drug effectsABSTRACT
Under the influence of polysorb in its application, adhesion of a gauze dressing to the wound surface reduces 3-fold. The in vitro investigations have shown that polysorb had a stimulating effect on fibrinolysis.
Subject(s)
Disease Models, Animal , Occlusive Dressings , Polymers/pharmacology , Skin Transplantation/methods , Wounds and Injuries/surgery , Adhesiveness , Animals , Female , Fibrinolysis/drug effects , In Vitro Techniques , Male , Postoperative Care , Rats , Stimulation, Chemical , Wound Healing/drug effects , Wounds and Injuries/bloodABSTRACT
The analysis of 161 case record of the patients with purulent-inflammatory diseases was carried out. The dependence of duration of treatment on the age of a patient, character of pathology, body temperature, leukocytic count, presence of pathologic changes in the urine was established. The expediency to limit antibiotic therapy in purulent-inflammatory diseases is substantiated.
