1.
Lancet
; 354(9186): 1266-7, 1999 Oct 09.
Article
in English
| MEDLINE
| ID: mdl-10520643
ABSTRACT
Two patients with chloracne had concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of 144,000 and 26,000 pg/g blood lipids. Olestra, a non-digestible, lipophilic dietary fat substitute accelerated the patients' intestinal excretion of TCDD by eight to ten fold. This is sufficient to reduce the normally observed elimination half life of TCDD from about 7 years to 1-2 years.
Subject(s)
Acne Vulgaris/drug therapy , Dietary Fats/therapeutic use , Environmental Pollutants/adverse effects , Environmental Pollutants/blood , Fatty Acids/therapeutic use , Polychlorinated Dibenzodioxins/adverse effects , Polychlorinated Dibenzodioxins/blood , Sucrose/analogs & derivatives , Acne Vulgaris/blood , Acne Vulgaris/chemically induced , Adult , Body Burden , Dietary Fats/administration & dosage , Dose-Response Relationship, Drug , Environmental Pollutants/pharmacokinetics , Fatty Acids/administration & dosage , Feces/chemistry , Female , Half-Life , Humans , Metabolic Clearance Rate , Polychlorinated Dibenzodioxins/chemistry , Polychlorinated Dibenzodioxins/pharmacokinetics , Sucrose/administration & dosage , Sucrose/therapeutic use
2.
Oral Oncol
; 34(4): 309-12, 1998 Jul.
Article
in English
| MEDLINE
| ID: mdl-9813728
ABSTRACT
Three cases of basal cell carcinomas (BCCs) of the vermilion zone of the lower lip are reported. The possible histopathogenesis of these BCCs is discussed. All lesions were treated by Mohs micrographic surgery.
Subject(s)
Carcinoma, Basal Cell/pathology , Lip Neoplasms/pathology , Microsurgery/methods , Aged , Aged, 80 and over , Carcinoma, Basal Cell/surgery , Female , Humans , Lip Neoplasms/surgery , Male
3.
J Am Acad Dermatol
; 37(3 Pt 1): 488-9, 1997 Sep.
Article
in English
| MEDLINE
| ID: mdl-9308568
