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1.
Reproductive characteristics and corticoid levels of female white-footed mice fed ad libitum and restricted diets containing a polychlorinated biphenyl.
Sanders, O T; Kirkpatrick, R L.
Environ Res ; 13(3): 358-63, 1977 Jun.
Article in English | MEDLINE | ID: mdl-407075

Subject(s)
Adrenal Cortex Hormones/blood , Aroclors/pharmacology , Polychlorinated Biphenyls/pharmacology , Reproduction/drug effects , Animals , Aroclors/administration & dosage , Body Weight/drug effects , Diet , Drug Interactions , Estrus/drug effects , Female , Genitalia, Female/drug effects , Mice , Organ Size/drug effects , Pentobarbital/pharmacology , Pregnancy , Sleep/drug effects , Time Factors
2.
Polychlorinated biphenyls and nutritional restriction: their effects and interactions on endocrine and reproductive characteristics of male white mice.
Sanders, O T; Kirkpatrick, R L; Scanlon, P E.
Toxicol Appl Pharmacol ; 40(1): 91-8, 1977 Apr.
Article in English | MEDLINE | ID: mdl-405757

Subject(s)
Aroclors/pharmacology , Endocrine Glands , Food Deprivation , Polychlorinated Biphenyls/pharmacology , Reproduction , Adrenal Cortex Hormones/blood , Adrenal Glands/drug effects , Adrenal Glands/physiology , Animals , Body Weight/drug effects , Endocrine Glands/drug effects , Endocrine Glands/physiology , Genitalia, Male/drug effects , Genitalia, Male/physiology , Liver/drug effects , Liver/physiology , Male , Mice , Organ Size/drug effects , Pentobarbital/pharmacology , Reproduction/drug effects , Sleep/drug effects , Spermatozoa/drug effects , Time Factors
3.
Effects of a polychlorinated biphenyl (PCB) on sleeping times, plasma corticosteroids, and testicular activity of white-footed mice.
Sanders, O T; Kirkpatrick, R L.
Environ Physiol Biochem ; 5(5): 308-13, 1975.
Article in English | MEDLINE | ID: mdl-811460

ABSTRACT

Forty adult male white-footed mice (Peromyscus leucopus) were divided into four equal groups and fed diets containing 0, 100, 200 or 400 p.p.m. of a polychlorinated biphenyl (PCB) for 2 weeks. PCB ingestion increased liver weights and reduced pentobarbital-induced sleeping times at all levels tested, indicating increased hepatic microsomal enzyme activity. Plasma corticoid levels, seminal vesicle weights and testicular spermatozoa numbers were reduced at the 400 p.p.m. level.


Subject(s)
Adrenal Cortex Hormones/blood , Microsomes, Liver/enzymology , Polychlorinated Biphenyls/pharmacology , Sleep/drug effects , Testis/drug effects , Adrenal Glands/drug effects , Animals , Body Weight/drug effects , Liver/drug effects , Male , Mice , Organ Size/drug effects , Species Specificity
4.
Reduction of pentobarbital-induced sleeping times in PCB-treated cottontail rabbits.
Zepp, R L; Sanders, O T; Kirkpatrick, R L.
Bull Environ Contam Toxicol ; 12(5): 518-21, 1974 Nov.
Article in English | MEDLINE | ID: mdl-4215523

Subject(s)
Pentobarbital/pharmacology , Polychlorinated Biphenyls/pharmacology , Animals , Diet , Female , Male , Microsomes, Liver/enzymology , Pentobarbital/antagonists & inhibitors , Rabbits , Sleep , Time Factors
5.
Effect of PCB ingestion on sleeping times, organ weights, food consumption, serum corticosterone and survival of albino mice.
Sanders, O T; Zepp, R L; Kirkpatrick, R L.
Bull Environ Contam Toxicol ; 12(4): 394-9, 1974 Oct.
Article in English | MEDLINE | ID: mdl-4215520

Subject(s)
Corticosterone/blood , Eating/drug effects , Genitalia, Male/drug effects , Polychlorinated Biphenyls/pharmacology , Sleep/drug effects , Adrenal Glands/drug effects , Animals , Body Weight , Dose-Response Relationship, Drug , Liver/drug effects , Male , Mice , Mice, Inbred ICR , Organ Size , Polychlorinated Biphenyls/toxicity , Testis/drug effects , Time Factors
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