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1.
Akush Ginekol (Sofiia) ; 55(2): 27-33, 2016.
Article in Bulgarian | MEDLINE | ID: mdl-27509654

ABSTRACT

Premature birth (PB) remains an unresolved problem, despite progress in prenatal medicine and the introduction of new methods and techniques of prolonged respiratory resuscitation in recent decades. Premature birth is the cause of 70% of neonatal mortality and 50% of long-term neurological complications in newborns, many of whom debilitating. Notwithstanding the significant progress prenatal care in the last twenty years in developed countries is a trend towards a gradual and continuous increase in premature births. PB is not only medical but also social problem. Despite the efforts of the scientific and practical obstetrics and modern tocolytic therapy, the rate of premature births in the last decade reduced. The causes of preterm birth are multifactorial and vary depending on gestational age, genetic factors and environmental factors. The long-term consequences of premature birth bear behind not only economic but also social problems. In many developing countries, premature birth is a major cause of disability. Clinical studies in recent years have been aimed at creating a comprehensive therapeutic algorithm behavior in premature births in order to reduce their frequency, especially for those born weighing less than 1000g.


Subject(s)
Premature Birth/epidemiology , Female , Humans , Infant , Infant Mortality , Infant, Newborn , Pregnancy , Premature Birth/mortality , Premature Birth/therapy , Risk Factors , Socioeconomic Factors
3.
Akush Ginekol (Sofiia) ; 55 Suppl 2: 14-18, 2016.
Article in Bulgarian | MEDLINE | ID: mdl-29470867

ABSTRACT

Premature birth (PB) occurs in 5% to 18% of births in the world. Children born prematurely are at increased risk of death, major neonatal complications, long-term adverse consequences for health and development. The cause of spontaneous preterm birth is often unknown, but it is believed that intrauterine infection is implicated in 40% of cases. The most likely route to intrauterine infection is ascending infection of the genital tract. Infection of the genital tract is more common in women with spontaneous preterm births in lower ge. tational age. s performed a retrospective research of 70 pregnant women and their newborns. In the group with preterm birth was reported high percentage of CVI - 37.14%, while in the control group this percentage is 17.14%. The results showed the increase in the incidence of CVI group of PB more than twice. There is a need an effective prevention and treatment of CVI during pregnancy. The timely detection of deviations from normal vaginal microflora and the correct therapeutic approach would reduce the risks of PB and infectious complications in newborns.


Subject(s)
Pregnancy Complications, Infectious/epidemiology , Premature Birth/epidemiology , Adult , Bulgaria/epidemiology , Candida albicans/isolation & purification , Candidiasis, Vulvovaginal/epidemiology , Candidiasis, Vulvovaginal/microbiology , Cervix Uteri/microbiology , Female , Humans , Infant, Newborn , Pregnancy , Pregnancy Complications, Infectious/microbiology , Retrospective Studies , Uterine Cervical Diseases/epidemiology , Uterine Cervical Diseases/microbiology , Vagina/microbiology , Vaginosis, Bacterial/epidemiology , Vaginosis, Bacterial/microbiology
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