Ectopia Cordis as a Lethal Neonatal Condition: A Case Report from Bahrain and a Literature Review.

Ectopia cordis is a rare type of malformation where the heart is not located normally. It may be partially or completely located outside the thoracic cavity and can be associated with other congenital abnormalities. It results from failure of maturation of midline mesoderm and ventral body formation during embryogenic formation. The exact etiology remains unknown. The literature review reveals the prognosis for infants with ectopia cordis is very poor. Here, we are reporting the first case of a fetus that was prenatally diagnosed with ectopia cordis that was associated with omphalocele documented in our country. Considering the poor prognosis for the fetus, conservative management during the prenatal period was chosen.

Dicephalus dibrachius with anencephaly.

We present a case of inferior conjunction in a rare type of conjoined twins, dicephalus in a male fetus. The male fetus was born to a 24-year-old, gravida 2, and para 0, who had medical abortion at 15 weeks of gestation due to anencephaly with meningoencephalocele revealed by ultrasound examination. The fetus was born with 2 anencephalic heads with a bifurcation of the vertebral column and presence of 2 spinal cords. The other viscera and limbs were normal in number and location as for a male singleton. This case illustrates the relationship between conjoined twining, and neural tube defect more particularly anencephaly with a male zygote, which is an unusual presentation for this type of zygote gender.

Small cell neuroendocrine carcinoma of the endometrium, a rare aggressive tumor.

This is a report of a young infertile woman with a history of 8 years amenorrhea, who presented with history of vaginal bleeding of 2 months duration. Investigations revealed a small cell neuroendocrine carcinoma of the endometrium, which penetrated half of the thickness of uterine wall. We have described the clinical progress and management of this rare and highly malignant cancer. A review of the pathological types and behavior of clear cell neuroendocrine carcinoma is presented.

Ruptured ovarian cysts and bilateral ectopic pregnancy complicating a case of severe ovarian hyperstimulation syndrome.

Ovarian hyperstimulation syndrome (OHSS), ruptured ovarian cysts and bilateral ectopic pregnancies are all well-recognized entities occurring in association with infertility treatment. We are reporting a case of severe OHSS which was complicated initially by ruptured ovarian cysts and later by bilateral ectopic pregnancy. Diagnosis of tubal pregnancy was obscured by stimulated ovaries, which prevented accurate ultrasound definition. The role of transvaginal ultrasound, serial beta human chorionic gonadotropin and the place of paracentesis in diagnosing these cases are discussed.