ABSTRACT
OBJECTIVES: To determine the frequency and associated factors of nasal colonization by Staphylococcus aureus and its antibiotic susceptibility pattern in a marginal suburban population Lima, Peru. MATERIALS AND METHODS: A cross-sectional study was conducted among population of all ages from a marginal suburban district in northern Lima. The study used a convenience sample. Each person was surveyed and provided a swab sample of the nostrils. The swab samples were analyzed to identify Staphylococcus aureus, determining the susceptibility pattern by the Kirby Bauer disk diffusion method. RESULTS: From the 452 participants recruited, ages between 1 and 84 years, the frequency of Staphylococcus aureus nasal colonization was 24.6%, with 0.9% of them resistant to methicillin. The only factor associated with nasal colonization was age equal or less than 11 years (OR: 3.80, 95% CI 1.42 to 10.16). Most strains were resistant to penicillin (96.4%) but also to erythromycin (10.9%), clindamycin (7.3%) and gentamicin (4.5%). CONCLUSIONS: The frequency of Staphylococcus aureus nasal colonization was similar to other studies worldwide, with predominance of methicillin-sensitive strains.
Subject(s)
Anti-Bacterial Agents/pharmacology , Staphylococcus aureus/drug effects , Adolescent , Adult , Aged , Aged, 80 and over , Carrier State , Child , Child, Preschool , Cross-Sectional Studies , Female , Humans , Infant , Male , Microbial Sensitivity Tests , Middle Aged , Nasal Cavity/microbiology , Peru , Staphylococcus aureus/isolation & purification , Suburban Health , Young AdultABSTRACT
Objetivos. Determinar la frecuencia y los factores asociados de la colonización nasal por Staphylococcus aureus, así como el patrón de susceptibilidad antibiótica en una población urbano marginal de Lima, Perú. Materiales y métodos. Estudio transversal en personas de cualquier edad provenientes de un distrito urbano marginal de la zona norte de la ciudad de Lima. El muestreo fue por conveniencia. A cada persona se le realizó una encuesta y se le tomó una muestra de hisopado de las narinas, las que fueron procesadas para la identificación de Staphylococcus aureus y determinación del patrón de susceptibilidad mediante el método de difusión de disco de Kirby Bauer. Resultados. De los 452 participantes reclutados, entre 1 y 84 años de edad, la frecuencia de colonización nasal de Staphylococcus aureus fue de 24,6%, de los cuales solo el 0,9% fue resistente a meticilina. El único factor asociado a la colonización nasal fue la edad menor o igual a 11 años (OR: 3,80; IC95%: 1,42 - 10,16). La mayoría de cepas fue resistente a la penicilina (96,4%) pero también se presentó a la eritromicina (10,9%), clindamicina (7,3%) y gentamicina (4,5%) en menor proporción. Conclusiones. La frecuencia de colonización nasal por Staphylococcus aureus fue similar a otros estudios a nivel mundial, con predominio de cepas meticilino sensibles.
Objectives. To determine the frequency and associated factors of nasal colonization by Staphylococcus aureus and its antibiotic susceptibility pattern in a marginal suburban population Lima, Peru. Materials and methods. A cross-sectional study was conducted among population of all ages from a marginal suburban district in northern Lima. The study used a convenience sample. Each person was surveyed and provided a swab sample of the nostrils. The swab samples were analyzed to identify Staphylococcus aureus, determining the susceptibility pattern by the Kirby Bauer disk diffusion method. Results. From the 452 participants recruited, ages between 1 and 84 years, the frequency of Staphylococcus aureus nasal colonization was 24.6%, with 0.9% of them resistant to methicillin. The only factor associated with nasal colonization was age equal or less than 11 years (OR: 3.80, 95% CI 1.42 to 10.16). Most strains were resistant to penicillin (96.4%) but also to erythromycin (10.9%), clindamycin (7.3%) and gentamicin (4.5%). Conclusions. The frequency of Staphylococcus aureus nasal colonization was similar to other studies worldwide, with predominance of methicillin-sensitive strains.
