ABSTRACT
The role of operative endoscopy as opposed to surgery in the treatment of obstructive jaundice is in continuous positive evolution due to the rapid technical progress made in the use of this method. Of a total of 93 patients treated over the course of 3 years, some received surgical treatment alone, others endoscopic treatment alone, and a third group received endoscopic therapy followed by surgery. Various parameters were taken into consideration for the three groups studied: the pathological cause of jaundice, age, sex, success of the method used, early and late complications, hospital deaths. Results were then compared.
Subject(s)
Cholestasis/surgery , Endoscopy , Age Factors , Aged , Drainage , Evaluation Studies as Topic , Female , Humans , Male , Middle Aged , Sex FactorsSubject(s)
Bile Duct Neoplasms/surgery , Cholestasis, Intrahepatic/surgery , Drainage/instrumentation , Endoscopy , Palliative Care , Prostheses and Implants , Aged , Bile Duct Neoplasms/complications , Cholangitis/etiology , Cholangitis/mortality , Cholestasis, Intrahepatic/etiology , Evaluation Studies as Topic , Female , Humans , Intraoperative Care , Italy/epidemiology , MaleABSTRACT
The importance of sexual hormones in the development of cancers of the large bowel is strongly supported experimentally and epidemiologically. The clinical search for the presence of hormonal receptors in the cells of patients operated for tumours of the colon and rectum has been common since 1975. This investigation ought to have opened up new diagnostic and therapeutic prospects for these tumours which have given such a little curative satisfaction. The present review considered reported data. Unfortunately the emerging picture is irregular in cases and results. It is personally considered that these studies are not for the moment likely to produce important novelties for the treatment of tumours of the large bowel tract.
Subject(s)
Colonic Neoplasms/metabolism , Neoplasms, Hormone-Dependent/metabolism , Receptors, Cell Surface/metabolism , Rectal Neoplasms/metabolism , Colonic Neoplasms/chemically induced , Colonic Neoplasms/pathology , Female , Humans , Male , Neoplasms, Hormone-Dependent/chemically induced , Neoplasms, Hormone-Dependent/pathology , Receptors, Steroid/metabolism , Rectal Neoplasms/chemically induced , Rectal Neoplasms/pathologyABSTRACT
An assay of Kininase II activity in the serum of 92 jaundice patients revealed a significant difference between the group with viral hepatitis (268.48 +/- 70.93 U/ml), that with biliary obstructions (133.05 +/- 37.64 U/ml) and with cirrhosis (173.76 +/- 79.56 U/ml). The increase encountered in patients with medical jaundice correlates well with total bilirubinaemia but not with cytolysis enzymes. This suggests failed demolition of ACE by the hepatocyte during cellular stress.
Subject(s)
Clinical Enzyme Tests , Jaundice/diagnosis , Peptidyl-Dipeptidase A/blood , Adolescent , Adult , Aged , Bilirubin/blood , Cholestasis/complications , Cholestasis/diagnosis , Cholestasis/etiology , Diagnosis, Differential , Female , Hepatitis, Viral, Human/complications , Hepatitis, Viral, Human/diagnosis , Humans , Jaundice/etiology , Liver Cirrhosis/complications , Liver Cirrhosis/diagnosis , Liver Function Tests , Male , Middle AgedSubject(s)
Cholelithiasis/surgery , Aged , Cholangiography , Cholecystectomy , Cholelithiasis/diagnosis , Endoscopy , Female , Humans , Male , Middle AgedABSTRACT
A group of 50 patients operated for carcinoma of the colon in June 1980-December 1981 with a follow-up period of min. 2 months-max. 15 months is presented. C.E.A. measurements were taken in all patients pre and post-operatively and then every 2 months in an attempt to establish its diagnostic and prognostic value. In immediate diagnostic and prognostic terms, pre-operative C.E.A. appears to be insignificant. However both pre-operative C.E.A. and C.E.A. at a distance of 6 months were found to be reliable for long term (max. 15 months) prognosis.
Subject(s)
Adenocarcinoma/diagnosis , Carcinoembryonic Antigen/analysis , Colonic Neoplasms/diagnosis , Adenocarcinoma/immunology , Adult , Aged , Binding, Competitive , Colonic Neoplasms/immunology , Female , Humans , Iodine Radioisotopes , Male , Middle Aged , PrognosisSubject(s)
Esophageal Neoplasms/therapy , Esophagus , Intubation , Adenocarcinoma/therapy , Aged , Carcinoma, Squamous Cell/therapy , Endoscopy , Female , Humans , Male , Middle Aged , Palliative CareABSTRACT
Leiomyosarcoma of rectum is a rather rare malignant tumour. Generally, it manifests late when pain, tenderness, rectal bleeding and obstruction occur or ulceration through the rectal mucose with bleeding or discharge occur. Rectal examination leads to the diagnosis of malignancy. The histological report confirms the type of tumor. A case of leiomyosarcoma of the rectum has been reported. Radical resection (Miles) is the treatment of choice at present. The prognosis is poor.
Subject(s)
Leiomyosarcoma/pathology , Rectal Neoplasms/pathology , Aged , Female , HumansABSTRACT
Clinical, radiological and endoscopic results at follow-up about 1-5 yr after surgery in a series of 62 patients subjected to Billroth I resection are compared with those in the literature. Recurrence of ulcers was observed in 8% (as opposed to 5% with the Billroth II). In addition, there was a marked reduction in the incidence of post-resection diseases, with less serious forms of dumping, sounder digestion, and smaller weight losses.
Subject(s)
Gastrectomy , Postgastrectomy Syndromes , Humans , Peptic Ulcer/surgery , Postoperative Complications , RecurrenceABSTRACT
Six cases of delayed rupture of the spleen in two stages are described. One case of occult rupture is also presented. A picture of acute anaemia was observed in the five two-stage cases, whereas the occult rupture was diagnosed as organised splenic haematoma following computerised scintiscanning, arteriography and tomography. Splenectomy was performed in all cases, under emergency conditions in the first five, and of choice in the sixth. No post-operative complications were noted.
