Wireless navigation of pigeons using polymer-based fully implantable stimulator: A pilot study using depth electrodes.

A polymer-based implantable stimulator for wirelessly navigating pigeons was conceptually suggested and a pilot study using depth electrodes was conducted. In this study, depth electrodes based on liquid crystal polymer (LCP) with eight channels were designed and fabricated. Electrochemical impedance spectrum (EIS) assessments were performed to measure impedances of the electrodes. The average value of the measured impedances was 16.8∠15.8 ° kµ. The electrodes were then advanced to a target nucleus (formatio reticularis medialis mesencephalic, FRM) of a pigeon to prove their in vivo feasibilities. Biphasic current pulses were generated by a custom-made stimulator and delivered to the electrodes to stimulate the FRM electrically. Pulses with an amplitude level of 0.567 µA, a rate of 58.0 Hz, and a duration of 1.00 ms were applied with inter-stimulus intervals of three minutes. Turning and circling behaviors were consistently shown when the FRM was stimulated. The feasibilities of the electrodes were proved in both in vitro and in vivo tests, as a pilot study for the suggested scheme. Finally, several discussions of the assessments and extensions for a fully implantable stimulator were described.

3D printed wire electrode carrier for a pilot study of the functional brain mapping.

In this paper, brain-machine interface (BMI) was adopted to investigate the motor area in the animal brain. Stainless steel wire electrodes were implanted to search the brain area for rotation, forward movement, and flapping. In continuation of our search for optimized coordinates for stimulation, we designed electrode case for safer transport and for a more accurate fabrication of the electrode array. The cases are customized for each set of coordinates, and quickly built using a 3D printer. The case reduced the surgery time and increased accuracy in electrode placement. Stimulation of various sites in the brain derived the pigeon to move as we have anticipated.

Determining the age of cats by pulp cavity/tooth width ratio using dental radiography

The purpose of this study was to evaluate the effect of age on the ratio of pulp cavity/tooth width (P/T ratio) in healthy cats. The dental radiographs of 32 cats (16 males and 16 females) were generated with a digital dental X-ray unit with the animals under general anesthesia. Standardized measurement of the canine teeth was performed by drawing a line on the radiograph perpendicular to the cementoenamel junction (CEJ) of the tooth. There was an inversely proportional correlation between chronological age and the P/T ratio. Moreover, a strong Pearson squared correlation (gamma2 = 0.92) was identified by the curved regression model. No significant differences in the P/T ratio based on gender or breed were found. These results suggest that determination of age by P/T ratio could be clinically useful for estimating the chronological age of cats.