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Br J Ophthalmol ; 93(5): 638-40, 2009 May.
Article in English | MEDLINE | ID: mdl-19098032

ABSTRACT

AIM: To compare retrobulbar haemodynamics and ipsilateral carotid wall thickness of patients with unilateral non-arteritic anterior ischaemic optic neuropathy (NAION) with their contralateral side. METHODS: Seventeen patients with unilateral NAION participated in this study. By means of Colour Doppler imaging, the blood-flow velocities of the ophthalmic artery were measured. Intima-media thickness (IMT) of common carotid and internal carotid arteries were measured using B-mode ultrasonography. Measurements of the affected side were compared with the non-involved side. RESULTS: Flow velocities in the ophthalmic arteries on the side of the eyes with NAION were significantly decreased compared with those on the side of the unaffected eyes (p<0.001). In addition, in all patients, both common and internal carotid artery IMT were significantly greater on the side of the NAION compared with the contralateral side (p<0.001). CONCLUSION: NAION may be associated with decreased retrobulbar flow velocities and increased carotid wall thickness.


Subject(s)
Carotid Arteries/pathology , Ophthalmic Artery/physiopathology , Optic Neuropathy, Ischemic/physiopathology , Aged , Blood Flow Velocity/physiology , Carotid Arteries/diagnostic imaging , Female , Hemodynamics/physiology , Humans , Male , Middle Aged , Optic Neuropathy, Ischemic/diagnostic imaging , Optic Neuropathy, Ischemic/pathology , Prospective Studies , Tunica Intima/diagnostic imaging , Tunica Intima/pathology , Tunica Media/diagnostic imaging , Tunica Media/pathology , Ultrasonography, Doppler, Transcranial/methods
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