Subject(s)
Humans , Male , Middle Aged , Asthenia/complications , Tuberculosis/complications , Tuberculosis/diagnosis , Low Back Pain/complications , Low Back Pain/etiology , Rifampin/therapeutic use , Isoniazid/therapeutic use , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Osteoarticular/drug therapy , Antitubercular Agents/therapeutic use , Tuberculosis/physiopathology , Asthenia/diagnosis , Tuberculosis , Low Back Pain , Odontoid Process/pathology , Lymphadenitis/complications , Lymphadenitis/diagnosis , Tuberculosis, Osteoarticular/physiopathology , Tuberculosis, OsteoarticularABSTRACT
Choriocarcinoma is an aggressive tumour. Uncommonly, it spreads distantly, and rarely results in pulmonary and brain metastases. Its prognosis is generally good when treated. We report a 33-year-old woman with fever, haemoptysis and asthenia. One month after the appearance of metrorrhagia, she was diagnosed to have choriocarcinoma with pulmonary metastasis. After chemotherapy, pulmonary images disappeared and human chorionic gonadotropin returned to normal. She was re-admitted with neurological signs ten months later, confirming recurrence of the disease with brain metastasis. She was treated with surgery and polychemotherapy, with a favourable outcome and disappearance of the disease.
Subject(s)
Brain Neoplasms/secondary , Brain Neoplasms/therapy , Choriocarcinoma/pathology , Gestational Trophoblastic Disease/pathology , Lung Neoplasms/secondary , Lung Neoplasms/therapy , Uterine Neoplasms/pathology , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Asthenia/etiology , Brain Neoplasms/diagnosis , Choriocarcinoma/diagnosis , Choriocarcinoma/therapy , Chorionic Gonadotropin/metabolism , Female , Gestational Trophoblastic Disease/diagnosis , Gestational Trophoblastic Disease/therapy , Hemoptysis/etiology , Humans , Lung Neoplasms/diagnosis , Neoplasm Metastasis , Pregnancy , Treatment Outcome , Uterine Neoplasms/diagnosis , Uterine Neoplasms/therapyABSTRACT
INTRODUCTION: Neurocysticercosis is a disease caused by infection of the central nervous system by the larva of Taenia solium whose main clinical manifestation is epileptic seizures. This disease, whose prevalence had decreased in Spain in previous decades, has been increasing in importance due to the increased migratory flows from endemic zones and international trips. A recent clinical case is presented to review the diagnostic criteria of this condition. CLINICAL CASE: 47 year old woman, native of Ecuador, with disease backgrounds of high blood pressure, who was admitted due to generalized tonic-clonic episodes. The neurological examination was consistent with normality. In the computed tomography (CT) scan images, several cystic lesions with scolex inside were observed. Positive results were obtained in the serology for Taenia solium in the cerebrospinal fluid. The CT scan lesion resolution was complete after completing cysticide treatment with albendazole. CONCLUSIONS: Neurocysticercosis should be considered as a diagnosis in all adult patients with epileptic seizures who have the epidemiological characteristics indicated.
Subject(s)
Epilepsy, Tonic-Clonic/etiology , Neurocysticercosis/complications , Ecuador , Emigration and Immigration , Epilepsy, Tonic-Clonic/diagnosis , Female , Humans , Middle Aged , Neurocysticercosis/diagnosis , SpainABSTRACT
Introducción. La neurocisticercosis es una patología producida por la infestación del sistema nervioso central por las formas larvarias de la Taenia solium, cuya principal manifestación clínica son las crisis epilépticas. Esta patología, cuya prevalencia había disminuido en España en las décadas previas, va incrementando su importancia debido al aumento de los flujos migratorios desde zonas endémicas y los viajes internacionales. Se presenta un caso clínico reciente para revisar los criterios diagnósticos de este proceso. Caso clínico. Paciente mujer de 47 años, natural de Ecuador, con antecedentes patológicos de hipertensión arterial, que ingresa por crisis tonicoclónica generalizada. La exploración neurológica fue compatible con la normalidad. En las imágenes de la tomografía computarizada (TC) se objetivaron varias lesiones quísticas con escólex en su interior. Se obtuvieron resultados positivos en la serología para Taenia solium en el líquido cefalorraquídeo. La resolución de las lesiones de la TC fue completa tras completar tratamiento cisticida con albendazol. Conclusiones. La neurocisticercosis debe plantearse como diagnóstico en todo paciente adulto con crisis epilépticas que presente las características epidemiológicas indicadas
Introduction. Neurocysticercosis is a disease caused by infection of the central nervous system by the larva of Taenia solium whose main clinical manifestation is epileptic seizures. This disease, whose prevalence had decreased in Spain in previous decades, has been increasing in importance due to the increased migratory flows from endemic zones and international trips. A recent clinical case is presented to review the diagnostic criteria of this condition. Clinical case. 47 year old woman, native of Ecuador, with disease backgrounds of high blood pressure, who was admitted due to generalized tonic-clonic episodes. The neurological examination was consistent with normality. In the computed tomography (CT) scan images, several cystic lesions with scolex inside were observed. Positive results were obtained in the serology for Taenia solium in the cerebrospinal fluid. The CT scan lesion resolution was complete after completing cysticide treatment with albendazole. Conclusions. Neurocysticercosis should be considered as a diagnosis in all adult patients with epileptic seizures who have the epidemiological characteristics indicated
Subject(s)
Female , Middle Aged , Humans , Neurocysticercosis/diagnosis , Epilepsy, Tonic-Clonic/diagnosis , Taenia solium/pathogenicity , Albendazole/therapeutic use , Transients and MigrantsSubject(s)
Hodgkin Disease/pathology , Lumbar Vertebrae/pathology , Thoracic Vertebrae/pathology , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Back Pain/etiology , Bleomycin/administration & dosage , Dacarbazine/administration & dosage , Doxorubicin/administration & dosage , Equatorial Guinea/ethnology , Female , Hodgkin Disease/complications , Hodgkin Disease/diagnosis , Hodgkin Disease/drug therapy , Humans , Middle Aged , Paraplegia/etiology , Spain , Spinal Cord Compression/etiology , Vinblastine/administration & dosageABSTRACT
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