Subject(s)
Cytomegalovirus Infections/complications , Heart Transplantation/immunology , Herpesvirus 6, Human , Herpesvirus 7, Human , Postoperative Complications/virology , Roseolovirus Infections/complications , Adult , Aged , Antigens, Viral/blood , Cytomegalovirus/isolation & purification , Cytomegalovirus Infections/epidemiology , DNA Primers , DNA, Viral/blood , DNA, Viral/isolation & purification , Drug Therapy, Combination , Female , Herpesvirus 6, Human/isolation & purification , Herpesvirus 7, Human/isolation & purification , Humans , Immunosuppressive Agents/therapeutic use , Leukocytes/virology , Male , Middle Aged , Polymerase Chain Reaction , Postoperative Complications/epidemiology , Roseolovirus Infections/epidemiologyABSTRACT
OBJECTIVE: The aim of this study was to determine the incidence of adult congenital anomalies of the coronary arteries over 31 years of angiographic studies, describing their angiographic and clinical characteristics. The results have been compared with the main series published. METHODS: The diagnostic angiographic reports done in the Principado de Asturias from 1968 to 1999 are reviewed. In those in which a congenital anomaly was diagnosed, the clinical report and the angiography were studied. The initial course of the anomaly was defined following angiographic criteria. RESULTS: Thirteen thousand five hundred reports were reviewed describing 75 patients with 75 anomalies (0.5%) including: anomalous origin of the left circumflex coronary artery (n = 24), coronary artery fistulae (n = 21), both coronary arteries arising from the left coronary sinus (n = 15), single coronary arteries (n = 6), both coronary arteries arising from the right coronary sinus (n = 2), separated origin of anterior descending and left circumflex coronary arteries (n = 3), anterior descending artery arising from the right coronary sinus (n = 2), and others (n = 1). Angiographic studies were done because of: angina (59%), dysnea (25%), atypical chest pain (7%), syncope (3%), dizziness (3%) and palpitations (3%). The initial course was retroaortic in all the circumflex arteries, interarterial in the right coronaries, anterior in the anterior descending arteries and retroaortic, septal and combined, in the left coronaries. CONCLUSIONS: Adult congenital anomalies of the coronary arteries are not very common and are usually casual findings of diagnostic angiographic studies. Left circumflex coronary artery anomalies are the most frequently diagnosed.
