ABSTRACT
In this study the authors' purpose was to observe the effects of surgical stress on the number of lymphocyte beta-adrenergic receptors in hypertensive and normotensive subjects. It was noticed that after surgery a significant reduction occurred in the number of binding sites of lymphocytes of both hypertensive and normotensive subjects. The time course of recovery to the pre-operative values of binding sites varied between the two groups, being slower in normotensive than in hypertensive patients. This might suggest a different pattern of regulation of the beta-adrenergic receptor between hypertensive and normotensive subjects.
Subject(s)
Lymphocytes/metabolism , Receptors, Adrenergic, beta/metabolism , Stress, Physiological/metabolism , Adult , Aged , Anesthesia , Cell Membrane/metabolism , Dihydroalprenolol , Female , Humans , Hypertension/blood , Male , Middle Aged , Surgical Procedures, OperativeSubject(s)
Anesthesia, Intravenous/adverse effects , Anesthetics/adverse effects , Drug Hypersensitivity , Aged , Bronchial Spasm/chemically induced , Drug Eruptions/etiology , Drug Hypersensitivity/etiology , Drug Hypersensitivity/prevention & control , Female , Humans , Hypotension/chemically induced , Male , Middle Aged , Respiratory Insufficiency/chemically inducedABSTRACT
Following mention of problems of cerebral haemodynamics and the action of various anaesthetics on endocranial pressure, a personal anaesthesiological technique based on the use of althesin in drip form is reported and its advantages listed.
