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Cassine, an antimicrobial alkaloid from Senna racemosa.

Sansores-Peraza, P; Rosado-Vallado, M; Brito-Loeza, W; Mena-Rejón, G J; Quijano, L.

Fitoterapia ; 71(6): 690-2, 2000 Dec.

Article in English | MEDLINE | ID: mdl-11077177

ABSTRACT

The leaves of Senna racemosa yielded the piperidine alkaloid cassine and an inositol methyl ether. Antimicrobial screening of the compounds revealed antibacterial activity of cassine with minimum inhibitory concentrations of 2.5 mg/ml for Staphylococcus aureus and Bacillus subtilis and 5.0 mg/ml for Candida albicans.

Subject(s)

Anti-Infective Agents/pharmacology , Ketones/pharmacology , Piperidines/pharmacology , Plant Extracts/pharmacology , Plants, Medicinal/chemistry , Anti-Bacterial Agents , Anti-Infective Agents/chemistry , Aspergillus niger/drug effects , Bacillus subtilis/drug effects , Candida albicans/drug effects , Escherichia coli/drug effects , Humans , Microbial Sensitivity Tests , Plant Extracts/chemistry , Plant Leaves/chemistry , Pseudomonas aeruginosa/drug effects , Staphylococcus aureus/drug effects

ABSTRACT

Subject(s)

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