ABSTRACT
Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We report the case of a 55-year-old man with a history of psoriasis vulgaris that has developed pemphigus foliaceus with pustules, triggered by withdrawal of systemic corticosteroids. This is the first report associating this atypical form of pemphigus with psoriasis, suggesting that an overlap with generalized pustular psoriasis can occur.
Subject(s)
Pemphigus/etiology , Pemphigus/pathology , Psoriasis/complications , Psoriasis/pathology , Biopsy , Dose-Response Relationship, Drug , Erythema/pathology , Glucocorticoids/therapeutic use , Humans , Male , Middle Aged , Pemphigus/drug therapy , Prednisone/therapeutic use , Psoriasis/drug therapy , Skin/pathologyABSTRACT
Abstract Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We report the case of a 55-year-old man with a history of psoriasis vulgaris that has developed pemphigus foliaceus with pustules, triggered by withdrawal of systemic corticosteroids. This is the first report associating this atypical form of pemphigus with psoriasis, suggesting that an overlap with generalized pustular psoriasis can occur.
Subject(s)
Humans , Male , Middle Aged , Psoriasis/complications , Psoriasis/pathology , Pemphigus/etiology , Pemphigus/pathology , Psoriasis/drug therapy , Skin/pathology , Biopsy , Prednisone/therapeutic use , Pemphigus/drug therapy , Dose-Response Relationship, Drug , Glucocorticoids/therapeutic useABSTRACT
Retalhos cutâneos constituem técnica cirúrgica particularmente útil para reparos estéticos nos casos de excisões extensas e/ou lesões de localizações peculiares, como a orelha. Diversas opções de retalhos cutâneos já foram descritas, determinando resultados variáveis que dependem do conhecimento teórico e da experiência prática do cirurgião. O objetivo deste artigo é relatar dois casos de sucesso com a utilização das técnicas de retalhos anterior e posterior para reparação da orelha e revisar a literatura afim.
The skin flaps are surgical techniques particularly useful to aesthetic repair in cases of extended excision and/or unusual sites, as in the ear. Many skin flaps options were already reported, resulting in variable results of the theoretical knowledge and practical experience of the surgeon. This article aims to describe two successful cases of ear reconstruction with the use of anterior and posterior flaps and to review the current literature.
ABSTRACT
Abstract Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of encapsulated cystic lesions in the dermis, with adjacent sebaceous gland. When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. This is the first case of steatocystoma multiplex suppurativa reported in the Brazilian literature. Female patient, 23 years old, with papular and nodular cystic lesions that started in the armpits and groin, later spreading to the trunk, lower limbs, anticubital fossa, face and scalp. The presence of papular-nodular lesions associated with disseminated hidradenitis-like lesions in flexural areas and the histopathological diagnosis of steatocystoma defined the diagnosis of steatocystoma multiplex suppurativa.
Subject(s)
Humans , Female , Young Adult , Steatocystoma Multiplex/pathology , Sebaceous Glands/pathology , Suppuration , Biopsy , Hidradenitis Suppurativa/pathology , Rare Diseases/pathology , Diagnosis, Differential , Epidermal Cyst/pathologyABSTRACT
Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of encapsulated cystic lesions in the dermis, with adjacent sebaceous gland. When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. This is the first case of steatocystoma multiplex suppurativa reported in the Brazilian literature. Female patient, 23 years old, with papular and nodular cystic lesions that started in the armpits and groin, later spreading to the trunk, lower limbs, anticubital fossa, face and scalp. The presence of papular-nodular lesions associated with disseminated hidradenitis-like lesions in flexural areas and the histopathological diagnosis of steatocystoma defined the diagnosis of steatocystoma multiplex suppurativa.