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Interact Cardiovasc Thorac Surg ; 8(3): 310-5, 2009 Mar.
Article in English | MEDLINE | ID: mdl-19050061

ABSTRACT

We evaluated the impact of immediate intra-aortic balloon pumping (IABP) on hospital and mid-term outcome of coronary artery bypass graft (CABG) whenever perioperative acute complications developed. We compared clinical, biochemical, echocardiographic in-hospital results and two-year follow-up outcome of 30 low-risk (EuroSCORE<5) CABG (group A) who immediately received perioperative IABP when acute complications were suspected, to a contemporary, uncomplicated case-matched group (30 patients; Group B). Two in-hospital deaths were recorded in group A with no deaths in controls (P=0.492). Group A showed significantly higher lactate only at ICU arrival (P=0.001). Troponin I was always higher, but never reached values diagnostic for myocardial infarction (P<0.001). Worse left ventricular ejection fraction (P<0.001) and wall motion score index (P=0.008) were recorded at ICU arrival in group A, although an almost complete recovery was registered at discharge. Two-year actuarial survival was similar between the two groups (P=0.598). No differences were observed in freedom from acute myocardial infarction (P=0.503) and from overall cardiac complications (P=0.410). Early IABP should be established whenever cardiac complications are suspected, because of its beneficial impact on enzymatic leakage, myocardial recovery at echocardiography, hospital outcome, mid-term follow-up survival and freedom from cardiovascular events.


Subject(s)
Cardiopulmonary Bypass/adverse effects , Coronary Artery Bypass/adverse effects , Intra-Aortic Balloon Pumping , Myocardial Stunning/surgery , Biomarkers/blood , Case-Control Studies , Critical Care , Echocardiography , Hospital Mortality , Humans , Intra-Aortic Balloon Pumping/adverse effects , L-Lactate Dehydrogenase/blood , Length of Stay , Myocardial Contraction , Myocardial Stunning/etiology , Myocardial Stunning/mortality , Myocardial Stunning/physiopathology , Perioperative Care , Recovery of Function , Retrospective Studies , Stroke Volume , Time Factors , Treatment Outcome , Troponin I/blood , Ventricular Function, Left
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