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Nat Prod Commun ; 10(11): 1955-8, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26749835

ABSTRACT

The biological activity of Ruta graveolens leaf tissue extracts obtained with different solvents (ethyl acetate, ethanol, and water) and metabolites (psoralen, 2- undecanone and rutin) against Spodoptera frugiperda was evaluated. Metabolites levels in extracts were quantified by HPLC and GC. Ethyl acetate and ethanol extracts showed 94% and 78% mortality, respectively. Additionally, psoralen metabolite showed a high mortality as cypermethrin. Metabolite quantification in extracts shows the presence of 2-undecanone (87.9 µmoles mg(-1) DW), psoralen (3.6 µmoles mg(-1) DW) and rutin (0.001 pmoles mg(-1) DW). We suggest that these concentrations of 2-undecanone and psoralen in R. graveolens leaf tissue extracts could be responsible for S. frugiperda mortality.


Subject(s)
Insecticides/pharmacology , Plant Extracts/pharmacology , Ruta/chemistry , Spodoptera/drug effects , Animals , Insecticides/chemistry , Insecticides/isolation & purification , Insecticides/metabolism , Plant Extracts/chemistry , Plant Extracts/isolation & purification , Plant Extracts/metabolism , Plant Leaves/chemistry , Plant Leaves/metabolism , Ruta/metabolism
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