ABSTRACT
Determinar qué porcentaje de una población sin dolor anterior de rodilla tiene un test de Zohlen positivo, además determinar el ángulo Q de esta población y buscar si existe alguna relación entre la positividad del test de Zohlen y alteraciones en el ángulo Q. Material y método: Estudio descriptivo-prospectivo observacional. Aplicación del test de Zohlen y medición del ángulo Q. La población se dividió en 2 grupos: test de Zohlen positivo y test de Zohlen negativo. Cuantificación y comparación de medias del ángulo Q en los dos grupos. Resultados: 90 sujetos evaluados, promedio de edad 20,18 años (18-40). Veinte sujetos (22,2 por ciento) con test de Zohlen positivo. Ángulo Q promedio en los sujetos con test de Zohlen negativo: 14,95°; ángulo Q promedio en los sujetos con test de Zohlen positivo: 16,9° (p < 0,05). Ángulo Q promedio en hombres con test de Zohlen negativo 13,4°; ángulo Q promedio en hombres con test de Zohlen positivo: 16° (p < 0,05). Ángulo Q promedio en mujeres con test de Zohlen negativo: 16,5°; ángulo Q promedio en mujeres con test de Zohlen positivo: 18°, sin diferencias estadísticamente significativas entre ambos grupos. Conclusiones: El test de Zohlen tiene una correlación positiva con el ángulo Q en sujetos de sexo masculino. Dada la correlación entre un ángulo Q alterado y la presencia de dolor anterior de rodilla, en los pacientes que presentan un test de Zohlen positivo sin haber consultado por dolor anterior de rodilla, la prevención primaria de dolor anterior de rodilla puede ser de utilidad...
To determine the percentage of a population without anterior knee pain with a positive Zohlen test, and also to determine the Q angle of this population and to determine if there is any relationship between the Zohlen test and Q angle anomalies. Methods:A prospective observational study was conducted in which Zohlen¿s test was applied and the Q angle was measured. The population was divided into 2 groups: Zohlen¿s positive and Zohlen¿s negative. Q angle was compared in the 2 groups. Results: The study included 90 subjects, with a mean age 20.18 years (18-40), of whom 20 subjects (22.2 percent) had positive Zohlen¿s test. The mean Q angle in subjects with negative Zohlen¿s test was 14.95°, and the mean Q angle in subjects with positive Zohlen¿s test was 16,9° (p<.05). The mean Q angle in men with negative Zohlen¿s test was 13.4°, and the mean Q angle in men with positive Zohlen¿s test was 16° (p < .05). The mean Q angle in women with negative Zohlen¿s test was 16.5°, with a mean Q angle of 18° in women with positive Zohlen¿s test, with no statistically significant differences found between groups. Conclusions: Zohlen¿s test has a positive correlation with the Q angle in male subjects. Given the correlation between the Q angle and the presence of anterior knee pain in patients who have a positive test without symptoms, primary prevention of anterior knee pain can be achieved...
Subject(s)
Humans , Male , Adolescent , Adult , Female , Young Adult , Knee/physiology , Knee/physiopathology , Patellofemoral Pain Syndrome/diagnosis , Patellofemoral Joint/physiology , Patellofemoral Joint/physiopathology , Arthralgia/diagnosis , Observational Study , Prospective StudiesSubject(s)
Cardiac Rehabilitation , Cardiovascular Diseases/prevention & control , Adult , Aged , Cardiology/standards , Cardiovascular Diseases/classification , Coronary Disease/classification , Coronary Disease/prevention & control , Coronary Disease/rehabilitation , Female , Humans , Latin America , Male , Middle Aged , Risk FactorsABSTRACT
In this document, the Inter-American Committee of Cardiovascular Prevention and Rehabilitation, together with the South American Society of Cardiology, aimed to formulate strategies, measures, and actions for cardiovascular disease prevention and rehabilitation (CVDPR). In the context of the implementation of a regional and national health policy in Latin American countries, the goal is to promote cardiovascular health and thereby decrease morbidity and mortality. The study group on Cardiopulmonary and Metabolic Rehabilitation from the Department of Exercise, Ergometry, and Cardiovascular Rehabilitation of the Brazilian Society of Cardiology has created a committee of experts to review the Portuguese version of the guideline and adapt it to the national reality. The mission of this document is to help health professionals to adopt effective measures of CVDPR in the routine clinical practice. The publication of this document and its broad implementation will contribute to the goal of the World Health Organization (WHO), which is the reduction of worldwide cardiovascular mortality by 25% until 2025. The study group's priorities are the following: • Emphasize the important role of CVDPR as an instrument of secondary prevention with significant impact on cardiovascular morbidity and mortality; • Join efforts for the knowledge on CVDPR, its dissemination, and adoption in most cardiovascular centers and institutes in South America, prioritizing the adoption of cardiovascular prevention methods that are comprehensive, practical, simple and which have a good cost/benefit ratio; • Improve the education of health professionals and patients with education programs on the importance of CVDPR services, which are directly targeted at the health system, clinical staff, patients, and community leaders, with the aim of decreasing the barriers to CVDPR implementation.
Com este documento, o Comitê Interamericano de Prevenção e Reabilitação Cardiovascular, em posição conjunta com a Sociedade Sul-Americana de Cardiologia, mostra seu interesse no desenvolvimento de estratégias, medidas e intervenções para a prevenção e a reabilitação cardiovascular. Com o objetivo de implementar na América Latina uma política de saúde regional e nacional dos países membros, tem-se o objetivo de promover a saúde cardiovascular e, consequentemente, diminuir a morbimortalidade. O grupo de estudos em Reabilitação Cardiopulmonar e Metabólica do Departamento de Exercício, Ergometria e Reabilitação Cardiovascular de Sociedade Brasileira de Cardiologia (DERC/SBC) criou uma comissão de experts para revisar a versão em português e adaptá-la à realidade nacional. Este documento tem como missão principal auxiliar os profissionais de saúde a alcançarem medidas efetivas de prevenção e reabilitação cardiovascular (RCV) na prática clínica diária. Com a difusão deste documento, bem como com a sua implementação de forma mais abrangente, contribuiremos com a meta da Organização Mundial de Saúde de diminuir a mortalidade cardiovascular no mundo em 25% até o ano de 2025. As prioridades deste grupo de trabalho são: • Enfatizar o caráter prioritário da RCV como instrumento de prevenção secundária com importante impacto na morbimortalidade cardiovascular; • Unir esforços para melhorar o conhecimento da RCV, sua difusão e aplicação na maioria dos centros e institutos cardiovasculares da América do Sul, priorizando a utilização de um método de prevenção cardiovascular integral, prático, de fácil aplicação e de custo/benefício comprovado; • Melhorar a educação do pessoal da saúde e dos pacientes por meio de programas educativos dirigidos, que permitam envolver diretamente os sistemas de saúde, pessoal médico, pacientes e líderes comunitários sobre a importância dos serviços de RCV, a fim de diminuir as barreiras para a sua implantação.
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Cardiovascular Diseases/prevention & control , Cardiovascular Diseases/rehabilitation , Cardiology/standards , Cardiovascular Diseases/classification , Coronary Disease/classification , Coronary Disease/prevention & control , Coronary Disease/rehabilitation , Latin America , Risk FactorsABSTRACT
INTRODUCTION: The aim of this study is to calculate the theoretical frequency of potential drug interactions (PDI) and their characteristics in the therapeutic plan of hospitalized patients in a Pediatric Intensive Care Unit (PICU). PATIENTS AND METHODS: An observational study was conducted which analyzed PICU prescriptions between September and November 2011. The inclusion criteria included to be hospitalized in a PICU, requirements of at least 3 drugs, except those topically applied, either gender, no age limit, no hospital stay required. The Micromedex® 2.0 program was used to detect and classify PDI. RESULTS: Of 223 patients, 100 met inclusion criteria, 610 prescriptions were analyzed and 815 drugs were prescribed. 1,240 PDI were detected in 44 patients; 12 patients received more than 10 drugs each, presenting 1,162 PDI (93.7% of total PDI). 8 patients were hospitalized for more than 10 days, presenting 1,035 PDI (83.5% of total PDI). According to PDI theoretical severity, 37.5% were high, 51.7% moderate, 6.7% low and 4.1% contraindicated. The therapeutic group most involved was antimicrobials (17.6%) and the most frequently involved individual drugs were chloral hydrate (15.9%), midazolam (14.1%) and vecuronium (13.4%). CONCLUSION: PDI were more frequent in patients associated with major polypharmacy and longer hospital stay.
Subject(s)
Drug Interactions , Intensive Care Units, Pediatric/statistics & numerical data , Polypharmacy , Prescription Drugs/adverse effects , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Length of Stay/statistics & numerical data , Male , Prescription Drugs/administration & dosageABSTRACT
La apendicitis aguda es la primera causa de cirugía en pediatría. Su manejo es de urgencia. Como complicación del proceso inflamatorio local se puede producir un plastrón apendicular, siendo este la principal causa de masa en fosa iliaca derecha asociada a cuadro clínico compatible; sin embargo, se debe considerar la ocurrencia de otras causas de masa local. El abordaje quirúrgico inmediato prima en el estudio de una masa en fosa iliaca derecha asociada a dolor local cuando se requiere llegar al diagnóstico con precisión, prefiriéndose antes que el abordaje diferido o conservador, usados con frecuencia cuando la sospecha principal es masa de origen apendicular.
The acute appendicitis is the first cause of surgery in pediatric care. Its management is urgent. As a complication of the local inflammatory process, it can develops an appendicular abscess, being this the principal cause of right fossa iliacs mass associated to clinic; nevertheless, it has to be considered other causes of local mass. The surgical approach goes first in the study of the right fossa iliacs mass associated to local pain when it is required to have a diagnosis with accuracy, preferring this before the interval appendicectomy or conservative management, frequently used when the principal hypothesis is an appendiceal mass.
Subject(s)
Humans , Male , Adolescent , Appendicitis/surgery , Appendicitis/diagnosis , Cecal Diseases/surgery , Cecal Diseases/diagnosis , Fecal Impaction/surgery , Fecal Impaction/diagnosisABSTRACT
We studied the role of Kupffer cell functioning in T3 liver preconditioning against ischemia-reperfusion (IR) injury using the macrophage inactivator gadolinium chloride (GdCl3) previous to T3 treatment. Male Sprague-Dawley rats given a single i.p. dose of 0.1 mg T3/kg were subjected to 1 h ischemia followed by 20 h reperfusion, in groups of animals pretreated with 10 mg GdCl3/kg i.v. 72 h before T(3) or with the respective vehicles. IR resulted in significant enhancement of serum aspartate aminotransferase (3.3-fold increase) and tumor necrosis factor-alpha (93% increase) levels, development of liver damage, and diminished nuclear factor-kappaB DNA binding over control values. These changes, which were suppressed by the T3 administration prior to IR, persisted in animals given GdCl3 before T3 treatment, under conditions of complete elimination of ED2+ Kupffer cells achieved in a time window of 72 h. It is concluded that Kupffer cell functioning is essential for T3 liver preconditioning, assessed in a warm IR injury model by hepatic macrophage inactivation.
