Fatal methemoglobinemia resulting from ingestion of isobutyl nitrite, a "room odorizer" widely used for recreational purposes.

The alkyl nitrites, specifically isobutyl nitrite, have taken a prominent place among those substances enjoying widespread recreational use, primarily in discotheques and in any toxicologically verified deaths, the chemical may cause fatal toxic methemoglobinemia if ingested. A case with a fatal outcome is presented, and the chemistry and toxicology of the substance are discussed.