ABSTRACT
A systematic review and network meta-analysis was carried out to assess the efficacy of different intrasocket interventions immediately after mandibular third molar surgery to prevent alveolar osteitis (AO). An electronic search was undertaken using EMBASE, Cochrane Library, MEDLINE/PubMed, Web of Science, Scopus, LILACS, and grey literature. We reviewed studies published up to September 2019 and included 37 randomized controlled trials (6175 mandibular third molar surgeries in 4716 patients). The pairwise meta-analysis showed that the incidence of AO decreased significantly when an intrasocket intervention was performed (risk ratio 0.39 [0.30, 0.52]; p < 0.0001). Platelet-rich fibrin (odds ratio 0.28; 95% CI [0.10, 0.71]), chlorhexidine gel 0.2% (0.52 [0.32, 0.95]), eugenol paste (0.06 [0.00, 0.77]), recombinant bovine growth factor (0.07 [0.00, 0.97]), colloidal silver gelatin sponge (0.05 [0.00, 0.74]), and acellular dermal matrix (0.04 [0.00, 0.74]) were significantly more effective than the placebo. Platelet-rich fibrin and chlorhexidine 0.2% gel had a large number of included studies and patients per comparison. Overall, there was moderate evidence to support the use of platelet-rich fibrin or chlorhexidine 0.2% gel in the socket for the prevention of AO after mandibular third molar surgery.
Subject(s)
Dry Socket , Tooth, Impacted , Animals , Cattle , Chlorhexidine , Humans , Molar , Molar, Third , Tooth ExtractionABSTRACT
As evidências científicas sugerem uma correlação entre os mecanismos imunopatogênicos entre artrite reumatoide e periodontite. Sendo assim, o objetivo do referido estudo é realizar uma revisão discutida da literatura da possível associação entre artrite reumatoide e periodontite sob aspectos epidemiológicos, biológicos e do impacto da intervenção de uma doença sobre a outra. O presente estudo considerou a associação entre a artrite reumatoide e a periodontite e concluiu que a possível associação, vista na revisão discutida da literatura entre essas doenças, referencia a importância da terapia periodontal na manutenção dos parâmetros de saúde oral e sistêmico...
Scientific evidence suggests a correlation between immunopathogenics mechanisms between rheumatoid arthrits and periodontitis. Therefore, the objective of this study is to conduct a review of the discussed possible association between rheumatoid arthrits and periodontitis literature, in epidemiological, biological and impact of the intervention of a disease on the other. This study considered the association between rheumatoid arthritis and periodontitis. The study concluded that the association, in the view discussed review of the literature between these diseases, reference the importance of periodontal therapy in the maintenance of oral and systemic health parameters...
