ABSTRACT
O artigo destaca a importância da higienização das mãos, considerada a ação isolada mais importante no controle de infecções em serviços de saúde. Aponta a falta de adesão dos profissionais de saúde a esta prática, constatada ao longo dos anos e objeto de estudos em diversas partes do mundo.
Subject(s)
Hand Disinfection , Health Promotion , 51920 , Health Education , Hygiene , Skin Care , Hygiene , Infection Control , SoapsABSTRACT
A construção racional do arsenal terapêutico, considerando a necessidade do paciente, a segurança e a disponibilidade do medicamento, e o melhor custo-benefício pressupõem embasamento na tríade: segurança, eficácia e qualidade. Mas na prática diária, a efetividade do medicamento é o que mais influencia a decisão do prescritor, que considera critérios que aumentem a adesão ao tratamento, tais como toxicidade relativa, conveniência de administração, custo e experiência de emprego. A entrada no mercado de novas moléculas para mesmos fins terapêuticos, acompanhada de grande publicidade, interfere no processo decisório do prescritor, assim como práticas de bonificações da indústria para venda nos balcões das farmácias repercutem na decisão de compra do paciente. O confronto entre a conhecida variabilidade biológica dos seres humanos e a não similaridade absoluta entre medicamentos da mesma classe terapêutica ou mesmo medicamentos genéricos, tem impacto na lista individualizada de medicamentos, que deve englobar os conceitos de droga de primeira escolha e segunda escolha. O desconhecimento desta discussão por parte dos prescritores é determinante do uso irracional de medicamentos, um problema de saúde publica. Assim, o objetivo do trabalho foi apresentar aos prescritores de medicamentos informações que possam auxiliar na construção mais racional do arsenal terapêutico utilizado para seus pacientes, com base em experiência na regulação de medicamentos da Agência Nacional de Vigilância Sanitária.
The rational construction of an essential drug list, considering the patient's need, drug safety, availability and the best cost-benefit ratio, is based on drug safety, efficacy and quality. However, in daily practice, the prescriber's decision is mostly influenced by drug effectiveness, following criteria that increase adherence to the treatment, such as relative drug toxicity, convenience, cost and prescriber's experience. In addition, frequent launching of new molecules for the same therapeutic indication, together with wide publicity targeting prescribers, interferes with the decision-making process. Similarly, the bonuses offered by the industry for over-the-counter drug sales interfere with the consumer's choice. The confrontation between known human biological variability and the knowledge that there is no absolute similarity between drugs of the same therapeutic class, or even generic drugs, has an impact on the prescriber's drug list, which should include the concept of first and second choice drugs. Prescribers' unfamiliarity with these subjects is a determinant factor for irrational drug use: a public health issue. The objective of this study was to introduce to drug prescribers information that can help them building up a rational drug list for their patients, based on the National Health Surveillance Agency (Anvisa) experience of drug regulation.
Subject(s)
Physician Self-Referral , Drugs, Generic , Drug Prescriptions , Similar , Drug UtilizationABSTRACT
The rational construction of an essential drug list, considering the patient's need, drug safety, availability and the best cost-benefit ratio, is based on drug safety, efficacy and quality. However, in daily practice, the prescriber's decision is mostly influenced by drug effectiveness, following criteria that increase adherence to the treatment, such as relative drug toxicity, convenience, cost and prescriber's experience. In addition, frequent launching of new molecules for the same therapeutic indication, together with wide publicity targeting prescribers, interferes with the decision-making process. Similarly, the bonuses offered by the industry for over-the-counter drug sales interfere with the consumer's choice. The confrontation between known human biological variability and the knowledge that there is no absolute similarity between drugs of the same therapeutic class, or even generic drugs, has an impact on the prescriber's drug list, which should include the concept of first and second choice drugs. Prescribers' unfamiliarity with these subjects is a determinant factor for irrational drug use: a public health issue. The objective of this study was to introduce to drug prescribers information that can help them building up a rational drug list for their patients, based on the National Health Surveillance Agency (Anvisa) experience of drug regulation.
