ABSTRACT
O avanço nas técnicas cirúrgicas de correção ou paliação das cardiopatias congênitas permitiu uma maior sobrevivência dos seus portadores. Porém, as complicações, como as arritmias, surgiram no seguimento destes pacientes; seja de forma precoce ou tardia no pós-operatório. Por outro lado, em algumas cardiopatias congênitas, as arritmias são complicações resultantes das modificações estruturais do miocárdio impostas pelos defeitos específicos. Este trabalho tem como objetivo discutir a importância dos eventos arrítmicos e morte súbita nas principais cardiopatias congênitas, tanto na sua evolução natural (sem correção cirúrgica), quanto no pós-operatório. Para isto, foi realizada uma revisão na literatura sobre o tema...
Subject(s)
Arrhythmias, Cardiac , Heart Defects, CongenitalABSTRACT
BACKGROUND: Increased body mass index (BMI) and waist circumference (WC) have been associated with blood pressure elevation. OBJECTIVE: To evaluate the effect of BMI and WC on blood pressure (BP) of adolescents. METHODS: Cross-sectional analytical study including 536 adolescents from public and private schools. BMI was calculated and classified as high-normal (> or =50th p and < 85th p), overweight (> or =85th p and < 95th p), and obesity (> 95th p). WC was measured and considered increased if > 75th p. BP was considered elevated if > 90th p. RESULTS: 319 (59.5%) adolescents were girls, the mean age was 14.0+/- 1.99 years, high-normal weight was found in 39.6%, overweight in 37.1% and obesity in 23.3%. The percentage of high SBP and DBP followed the increase in BMI (p=0.000), reaching 46.4% among boys and 39.3% among obese girls for SBP and 42.0% and 44.6% for DBP, respectively. High SBP and DBP were 3.9 and 3.4 times more frequent among boys and 2.2 to 2.0 times more frequent among girls with WC > 75th p, respectively. Using simple linear regression analysis, each increment in BMI would increase SBP by 1.198 mmHg, and in WC by 0.622 mmHg. The PR for elevated SBP and DBP in relation to BMI > or =85th p was 3.9 (95% CI 2.0-7.4[p=0.000]) and 4.3(95% CI 2.2-8.5[p=0.000]), respectively; in relation to WC > 75th p was 1.8(95% CI 1.0 to 3.0 [p=0.036]) and 1.4 (95% CI 0.8 to 2.4). BP > 90th p with WC < or =75th p was found in 16/181 (8.8%) of the adolescents with high-normal weight. CONCLUSION: BMI and WC values have a strong influence on BP values in adolescents.
Subject(s)
Blood Pressure/physiology , Body Mass Index , Hypertension/diagnosis , Obesity/diagnosis , Waist Circumference , Adolescent , Blood Pressure Determination , Brazil/epidemiology , Child , Female , Humans , Hypertension/epidemiology , Hypertension/etiology , Linear Models , Male , Obesity/epidemiologyABSTRACT
FUNDAMENTO: Aumento do índice de massa corporal (IMC) e da circunferência abdominal (CA) tem sido associado a elevação da pressão arterial. OBJETIVO: Avaliar o efeito do IMC e da CA sobre a pressão arterial (PA) de adolescentes. MÉTODOS: Estudo analítico de corte transversal. Selecionados 536 adolescentes, alunos de escolas públicas e privadas. Foram calculados IMC, classificado como normal alto (>p50
BACKGROUND: Increased body mass index (BMI) and waist circumference (WC) have been associated with blood pressure elevation. OBJECTIVE: To evaluate the effect of BMI and WC on blood pressure (BP) of adolescents. METHODS: Cross-sectional analytical study including 536 adolescents from public and private schools. BMI was calculated and classified as high-normal (> 50th p and < 85th p), overweight (> 85th p and < 95th p), and obesity (> 95th p). WC was measured and considered increased if > 75th p. BP was considered elevated if > 90th p. RESULTS: 319 (59.5 percent) adolescents were girls, the mean age was 14.0± 1.99 years, high-normal weight was found in 39.6 percent, overweight in 37.1 percent and obesity in 23.3 percent. The percentage of high SBP and DBP followed the increase in BMI (p=0.000), reaching 46.4 percent among boys and 39.3 percent among obese girls for SBP and 42.0 percent and 44.6 percent for DBP, respectively. High SBP and DBP were 3.9 and 3.4 times more frequent among boys and 2.2 to 2.0 times more frequent among girls with WC > 75th p, respectively. Using simple linear regression analysis, each increment in BMI would increase SBP by 1.198 mmHg, and in WC by 0.622 mmHg. The PR for elevated SBP and DBP in relation to BMI > 85th p was 3.9 (95 percent CI 2.0-7.4[p=0.000]) and 4.3(95 percent CI 2.2-8.5[p=0.000]), respectively; in relation to WC > 75th p was 1.8(95 percent CI 1.0 to 3.0 [p=0.036]) and 1.4 (95 percent CI 0.8 to 2.4). BP > 90th p with WC < 75th p was found in 16/181 (8.8 percent) of the adolescents with high-normal weight. CONCLUSION: BMI and WC values have a strong influence on BP values in adolescents.
Subject(s)
Adolescent , Child , Female , Humans , Male , Body Mass Index , Blood Pressure/physiology , Hypertension/diagnosis , Obesity/diagnosis , Waist Circumference , Blood Pressure Determination , Brazil/epidemiology , Hypertension/epidemiology , Hypertension/etiology , Linear Models , Obesity/epidemiologyABSTRACT
AIM: To evaluate the sensitivity and specificity of abdominal ultrasound (US) for the diagnosis of hepatic steatosis in severe obese subjects and its relation to histological grade of steatosis. METHODS: A consecutive series of obese patients, who underwent bariatric surgery from October 2004 to May 2005, was selected. Ultrasonography was performed in all patients as part of routine preoperative time and an intraoperative wedge biopsy was obtained at the beginning of the bariatric surgery. The US and histological findings of steatosis were compared, considering histology as the gold standard. RESULTS: The study included 105 patients. The mean age was 37.2+/-10.6 years and 75.2% were female. The histological prevalence of steatosis was 89.5%. The sensitivity and specificity of US in the diagnosis of hepatic steatosis were, respectively, 64.9% (95% CI: 54.9-74.3) and 90.9% (95% CI: 57.1-99.5). The positive predictive value and negative predictive value were, respectively, 98.4% (95% CI: 90.2-99.9) and 23.3% (95% CI: 12.3-39.0). The presence of steatosis on US was associated to advanced grades of steatosis on histology (P=0.016). CONCLUSION: Preoperative abdominal US in our series has not shown to be an accurate method for the diagnosis of hepatic steatosis in severe obese patients. Until another non-invasive method demonstrates better sensitivity and specificity values, histological evaluation may be recommended to these patients undergoing bariatric surgery.
Subject(s)
Abdomen/diagnostic imaging , Fatty Liver/complications , Fatty Liver/diagnostic imaging , Obesity, Morbid/complications , Adult , Bariatric Surgery , Biopsy , Female , Humans , Liver/diagnostic imaging , Liver/pathology , Male , Middle Aged , Obesity, Morbid/surgery , Prevalence , Reproducibility of Results , Sensitivity and Specificity , Severity of Illness Index , UltrasonographyABSTRACT
BACKGROUND: Obesity has been shown to be an important risk factor for several gastrointestinal diseases. However, the indication for preoperative upper gastrointestinal endoscopy (UGE) for all patients before bariatric surgery is controversial. The aim of the present study was to evaluate the spectrum of gastrointestinal diseases detected during preoperative UGE in patients undergoing bariatric surgery and the relevance of this procedure. METHODS: A series of severely obese patients, who had undergone UGE before Roux-en-Y gastric bypass from October 2004 to May 2005 were consecutively enrolled in this study. The demographic and clinical data and endoscopic diagnoses were evaluated. Gastric biopsies were performed in elective patients according to the endoscopic findings. RESULTS: The study included 162 patients, 69.8% of whom were women. The mean age was 36.7 +/- 10.8 years. Abnormal findings were observed in 77.2% of patients. Esophagitis was present in 38.9%, gastritis in 51.2% (erosive gastritis in 49.3% and nonerosive gastritis in 50.7%), gastric ulcers in 1.9%, hiatal hernia, in 8.6%, gastric polyp in .6%, and duodenitis in 6.8% of patients. No patient had esophageal or gastric varices. Helicobacter pylori infection was investigated in 96 patients and was detected in 37.5%. Gastric biopsies were performed in 36 patients, with chronic inflammation found in 72.2%, inflammatory activity in 30.6%, and intestinal metaplasia in 11.1%. Glandular atrophy was not found in any patient. CONCLUSION: The results of our study have shown that the spectrum of gastrointestinal diseases observed in severely obese patients who underwent bariatric surgery is broad. Although this issue remains highly controversial, these findings suggest that systematic preoperative UGE and H. pylori testing should be performed in all patients scheduled to undergo bariatric surgery.
