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1.
Aust Vet J ; 98(9): 442-448, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32743816

ABSTRACT

SnakeMap is a national cloud-based, veterinary snakebite registry. It was designed to prospectively collect data of the clinical circumstances and temporospatial information on cases of snake envenomation in dogs and cats. We herein introduce the project and summarise the data from the first 4 years of SnakeMap. The registry is a veterinary community-based online database allowing case entry from veterinary hospitals across Australia. Registry data comprise hospital characteristics, patient characteristics, envenoming snake type, treatment and outcome variables, including time and geolocation of the snake bite. We present summative information on select key variables from the SnakeMap registry (1 July 2015 to 30 June 2019). Twenty-eight hospitals from 6 states/territories entered 624 cases into the registry, including 419 dogs (67%) and 205 cats (33%). Bite time was available in 216 animals of which 90 (42%) were reported to be bitten in the 3 hours between 03:00 pm and 05:59 pm; median bite to presentation interval was 60 (interquartile range [IQR] 30, 211) minutes in dogs and 95 (IQR 41, 238) minutes in cats. Bites occurred in the owner's yard in 356 dogs (85%) and 53 cats (26%). A snake venom detection kit was used in 172 cases (28%) and antivenom was administered in 523 cases (85%). Most animals (n = 534, 88%) survived to discharge (median hospitalisation of 25 [IQR 16, 62] hours). SnakeMap effectively collects relevant clinical data from dogs and cats with presumed snake bite and provides locally specific information on the epidemiology of snake envenomation in small animals.


Subject(s)
Cat Diseases , Dog Diseases , Snake Bites/veterinary , Animals , Antivenins , Australia , Cats , Dogs , Elapidae , Registries
2.
N Z Vet J ; 66(2): 79-84, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29129149

ABSTRACT

AIMS: To evaluate the quality of anaesthesia and cardiorespiratory effects of ketamine and two doses of dexmedetomidine in captive black capuchin monkeys (Sapajus nigritus) undergoing routine clinical examination. METHODS: Twenty-four animals undergoing routine clinical examination were enrolled in the study. Animals were briefly physically restrained and examined to ensure no obvious illness was present and that they were healthy. Monkeys were randomly allocated to two groups (n=12 per group) and then treated with a combination of I/M 7.5 mg/kg ketamine and either 30 µg/kg or 50 µg/kg dexmedetomidine (Dex30 or Dex50 groups, respectively). Interval to onset and duration of anaesthesia were recorded, and the quality of induction of anaesthesia and recovery were subjectively evaluated. Heart rate, respiratory rate, systolic arterial pressure (SAP), rectal temperature, degree of sedation, analgesia, muscle relaxation and response to auditory stimulus were measured every 5 minutes from onset of anaesthesia until recovery. RESULTS: The mean interval to onset of anaesthesia was 7.3 (SD 6.6) and 9.1 (SD 5.0) minutes for the Dex30 and Dex50 groups, respectively (p=0.208). Mean duration of anaesthesia was longer for monkeys in the Dex50 (85.5 (SD 15.3) minutes) compared to those in Dex30 (63.9 (SD 16.4) minutes) group (p=0.003). Induction was considered excellent in 23/24 animals, and recovery was excellent in all animals. Heart rate, respiratory rate and body temperature decreased in both groups when compared to baseline, with no differences between groups. No differences between groups were found for assessments of sedation, analgesia, muscle relaxation or response to auditory stimulus. CONCLUSION AND CLINICAL RELEVANCE: Administration of ketamine and dexmedetomidine at the two doses produced adequate, dose-dependent chemical restraint, with excellent induction and recovery, and minimal clinically significant cardiorespiratory effects in captive capuchin monkeys. Due to the occurrence of arrhythmias, electrocardiographic monitoring is recommended when this combination is used. The administration of higher doses of dexmedetomidine produced longer lasting anaesthesia without further compromise of cardiorespiratory parameters.


Subject(s)
Anesthetics, Dissociative/pharmacology , Dexmedetomidine/pharmacology , Heart Rate/drug effects , Hypnotics and Sedatives/pharmacology , Ketamine/pharmacology , Respiratory Rate/drug effects , Animals , Brazil , Cebus , Dose-Response Relationship, Drug , Drug Combinations , Female , Male , Monitoring, Physiologic/veterinary , Random Allocation
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