ABSTRACT
BACKGROUND: Studies have demonstrated that the combination of Nintendo Wii (NW) with Conventional Exercises (CE) was effective in the rehabilitation of patients with Parkinson's Disease (PD), but there are no studies comparing the effects of this combination on both techniques isolated. OBJECTIVE: To investigate if the effects of the combination of NW to CE are superior to isolated techniques in the rehabilitation of balance, gait, functional mobility and improvement of the quality of life of individuals with PD. METHODS: 45 patients with PD were divided into three groups, NW alone, CE alone and NW plus EC. The sessions occurred for 50 minutes, twice a week and evaluations administered before and after the 2-month intervention. RESULTS: Significant differences were found in the pre and post intervention analyzes of all the outcomes in the three groups, but there was no difference between the groups. The effect size was evaluated, in which the NW plus CE group had a greater magnitude of the therapeutic effect. CONCLUSION: The NW plus CE was statistically as effective as each intervention alone in the rehabilitation of patients with PD, however, the use of this combination provided a magnitude of the therapeutic effect superior to the other groups.
Subject(s)
Exercise Therapy/methods , Neurological Rehabilitation/methods , Parkinson Disease/rehabilitation , Play Therapy/methods , Video Games , Aged , Female , Gait , Humans , Male , Middle Aged , Postural Balance , Quality of Life , Single-Blind MethodABSTRACT
BACKGROUND: Randomized clinical trials (RCTs) used the Nintendo Wii (NW) in the treatment of Parkinson Disease, however, no meta-analysis was developed to determine the effects in these patients. OBJECTIVE: To analyze RCTs that investigated the effects of NW versus traditional physiotherapy on balance rehabilitation and quality of life of patients with PD. METHODS: Electronic research was conducted between December 2018 and January 2019 in the MEDLINE, PEDro, CENTRAL, LILACS and SciELO databases. The methodological quality was evaluated by the PEDro scale and the completeness of the description of the interventions by the TIDieR checklist. Weighted mean differences (WMD) and 95% confidence interval (CI) were calculated. RESULTS: Five studies were included and presented an average of 5.4 (1.5) on the PEDro scale and 6.7 (1.4) on the TIDieR. Compared to traditional physiotherapy, combined NW and traditional physiotherapy resulted in improvement in balance WMD 1.24 (95% CI: CI: 0.2 to 2.3 Nâ=â72) and quality of life WMD- 8.9 (95% CI: -15.2 to -2.6 Nâ=â56). CONCLUSION: combined NW and traditional physiotherapy was more effective on balance rehabilitation and quality of life of patients with PD, but the values demonstrated a poor methodological quality and a low level of completeness of the intervention descriptions.
Subject(s)
Exercise Therapy/methods , Exercise Therapy/psychology , Parkinson Disease/psychology , Parkinson Disease/rehabilitation , Postural Balance/physiology , Video Games/psychology , Humans , Parkinson Disease/physiopathology , Quality of Life/psychology , Treatment OutcomeABSTRACT
Objetivo: identificar, na literatura, os fatores de risco associados às síndromes hipertensivas da gestação. Método: revisão integrativa, realizada a partir das bases de dados LILACS, MEDLINE, CUMED, BDENF e IBECS, com artigos publicados no período de 2000 a 2016, utilizando os descritores em Saúde: Hipertensão gestacional e Fatores de risco, com a amostra final constituída por 17 produções. Resultados: Observou-se prevalência da Base de Dados LILACS, totalizando 11 (64,7%) artigos, com nove (52,9%) de língua portuguesa; nível de evidência IV em oito (47,06%) dos periódicos e estudos publicados no ano de 2014 com quatro (23,5%)produções. Conclusão: os resultados permitiram identificar os seguintes fatores de risco para SHEG: idades extremas; raça não branca; nível socioeconômico e demográfico desfavorável; antecedentes pessoais e familiares para PE; sobrepeso; nutrição inadequada; hipertensão arterial crônica e DM.
Subject(s)
Female , Humans , Pregnancy , Pregnancy Complications , Pregnancy, High-Risk , Hypertension, Pregnancy-Induced , Maternal Health , MEDLINE , Obstetric NursingABSTRACT
BACKGROUND: To evaluate the effectiveness of the video game console Nintendo Wii (NW) in motor function, balance, and functional independence in the treatment of poststroke patients and to identify which games are commonly used in therapy. METHODS: Randomized controlled trials were researched in MEDLINE, Cochrane Library, PEDro, CAPES Periodic, BIREME, and LILACS databases, covering publications up to March 31, 2014. The assessment of methodological quality was performed using the PEDro Scale as reference. RESULTS: The 5 studies included for analysis showed that NW can provide an improvement of motor function of the individual, but the data are unclear when it comes to the balance and functional independence. CONCLUSIONS: It was concluded that there is little evidence to ensure the effectiveness and support the inclusion of the treatment with NW in patients with sequelae caused by a stroke; however, some of the studies analyzed suggest that NW can provide improvement in motor function.
Subject(s)
Stroke Rehabilitation , Therapy, Computer-Assisted/methods , Video Games , Humans , MEDLINE/statistics & numerical data , Randomized Controlled Trials as Topic , Stroke/physiopathologyABSTRACT
Doença de Parkinson (DP) é caracterizada por uma perda seletiva e profunda dos neurônios dopaminérgicos da substância nigra pars compacta (SNpc) do mesencéfalo, acompanhada pela espoliação de dopamina no corpo estriado. A maioria dos casos de DP apresenta etiologia multifatorial, com a presença de componentes genéticos e ambientais. Embora existam diferentes causas possíveis, a patogênese da desordem parece convergir para mecanismos relacionados à disfunção mitocondrial, estresse oxidativo e mau enovelamento proteico. Um modelo estabelecido na literatura para estudo desta doença, tanto in vitro quanto in vivo é a administração de rotenona, um pesticida derivado de plantas que inibe o complexo I mitocondrial e favorece a geração de espécies reativas de oxigênio (ERO), levando a uma espoliação de glutation reduzido (GSH) através do processo de detoxificação destes compostos eletrofílicos, catalisados por glutation S-transferases (GSTs). Sendo assim, a busca por novas substâncias com atividade neuroprotetora é atualmente o foco de estudos, e metabólitos isolados de plantas podem ser fontes destas moléculas. Dessa forma, o 8-metoxipsoraleno (8-MOP), uma furocumarina, foi testado como um possível agente protetor sobre a citotoxicidade causada pela rotenona em modelos in vitro de gliomas, considerando o papel do glutation neste processo. O estudo adotou uma abordagem que associa técnicas bioquímicas e de biologia celular. Ensaios de viabilidade celular foram realizados em células de glioma murino (C6) e glioblastoma multiforme humano (U251) através da redução do brometo de 3-(4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolium (MTT)...
Parkinsons disease (PD) is characterized by a profound and selective loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) accompanied by midbrain dopamine depletion in the striatum. Most cases of PD present multifactorial etiologies, with the presence of genetic and environmental components. Although there are different possible causes, the pathogenesis of the disorder seems to converge to mechanisms related to mitochondrial dysfunction, oxidative stress and bad protein folding. An established model in the literature to study this disease, both in vitro and in vivo is rotenone administration, a pesticide derived from plants that inhibits the mitochondrial complex I and favors the generation of reactive oxygen species (ROS), leading to reduced glutathione (GSH) depletion through the detoxification process of this electrophilic compound catalyzed by glutathione S-transferases (GSTs). Thus, the search for new substances with neuroprotective activity is currently the focus of studies, and plant isolated metabolites can be sources of these molecules. Thus, 8-methoxypsoralen (8-MOP), a furocoumarin, was tested as a potential protective agent on the cytotoxicity caused by rotenone in glioma cells in vitro models, considering the role of glutathione in the process. The study adopted an approach that combines biochemical and cell biology techniques. Cell viability assays were performed in murine glioma cells (C6) and human glioblastoma (U251) cells through the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)...
Subject(s)
Humans , Parkinson Disease/diagnosis , Parkinson Disease/immunology , Parkinson Disease/pathology , Parkinson Disease/prevention & controlABSTRACT
O objetivo deste estudo foi avaliar o equilíbrio e o risco de quedas em idosos acometidos por Acidente Vascular Encefálico (AVE), atendidos no Núcleo Municipal de Prevenção e Reabilitação Física do Município de Jequié (NUPREJ), (Bahia). Foram utilizados como instrumentos o Mini-Exame do Estado Mental, um questionário sociodemográfico e a Escala de Equilíbrio de Berg. Os resultados evidenciaram uma diminuição do equilíbrio, indicando ser este um fator de risco para quedas.(AU)
The aim of this study was to evaluate the balance and risk of falls in elderly patients with Stroke treated at the Municipal Center for Prevention and Rehabilitation Physics of the Municipality of Jequié (NUPREJ), (Bahia). Instruments were used as the Mini Mental State Examination, a social demographic questionnaire and the Berg Balance Scale. The results showed a decrease in balance, indicating that this was a risk factor for falls.(AU)
Subject(s)
Humans , Aged , Stroke , Postural Balance , AgedABSTRACT
O objetivo deste estudo foi avaliar o equilíbrio e o risco de quedas em idosos acometidos por Acidente Vascular Encefálico (AVE), atendidos no Núcleo Municipal de Prevenção e Reabilitação Física do Município de Jequié (NUPREJ), (Bahia). Foram utilizados como instrumentos o Mini-Exame do Estado Mental, um questionário sociodemográfico e a Escala de Equilíbrio de Berg. Os resultados evidenciaram uma diminuição do equilíbrio, indicando ser este um fator de risco para quedas...
The aim of this study was to evaluate the balance and risk of falls in elderly patients with Stroke treated at the Municipal Center for Prevention and Rehabilitation Physics of the Municipality of Jequié (NUPREJ), (Bahia). Instruments were used as the Mini Mental State Examination, a social demographic questionnaire and the Berg Balance Scale. The results showed a decrease in balance, indicating that this was a risk factor for falls...
