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9.
Rheumatol Int ; 40(8): 1327-1332, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32533290

ABSTRACT

Crystalglobulinemia is an extremely rare pathology that is associated in most cases with plasma cell dyscrasia, mainly multiple myeloma. In most cases, it may be the manifestation of incipient gammopathy or it manifests shortly after diagnosis. We report a patient with ischemic lesions of thrombotic origin in lower limbs. Subsequently, renal involvement occurs, in view of this involvement, it is suspected that the patient may have an associated vasculitis. After performing the biopsy and with the subsequent diagnosis of monoclonal gammopathy of uncertain significance, the diagnosis is made. We review the most recent bibliography of patients who have been diagnosed with crystalglobulinemia associated with plasma dyscrasia focusing in those with thrombotic vasculopathy or acute renal failure. In our case, in addition to being associated with monoclonal gammopathy of undetermined significance that is less frequent, the debut of the symptoms is years before the detection of the monoclonal peak. This could speak of patients with a low peak of monoclonal component (not detected by immunoelectrophoresis) who could have kidney and vascular damage.


Subject(s)
Paraproteinemias/diagnosis , Acute Kidney Injury/etiology , Acute Kidney Injury/surgery , Adult , Delayed Diagnosis , Female , Humans , Kidney Transplantation , Monoclonal Gammopathy of Undetermined Significance/diagnosis , Multiple Myeloma/complications , Paraproteinemias/complications , Paraproteinemias/physiopathology , Thrombotic Microangiopathies/pathology
12.
Cir. Esp. (Ed. impr.) ; 67(3): 296-298, mar. 2000. ilus
Article in Es | IBECS | ID: ibc-3738

ABSTRACT

Presentamos un caso de metástasis pancreática de adenocarcinoma renal en una paciente intervenida hacía 14 años por un adenocarcinoma renal, en la revisión de su enfermedad se objetivó, en la ecografía y en la TAC, un nuevo adenocarcinoma renal en el riñón contralateral con un nódulo en cuerpo pancreático, siendo éste una metástasis de adenocarcinoma renal, que se confirmó con la PAAF. Se realizó una nefrectomía parcial y una resección corporocaudal pancreática por lumbotomía, no siendo el abordaje de elección pero permitiendo un buen campo para la resección pancreática parcial. Tras 20 meses de seguimiento, la paciente presenta una remisión total de su enfermedad (AU)


Subject(s)
Aged , Female , Humans , Pancreatectomy , Carcinoma, Renal Cell/secondary , Carcinoma, Renal Cell/complications , Pancreatic Neoplasms/diagnosis , Pancreatic Neoplasms/surgery , Pancreatic Neoplasms/secondary , Kidney Neoplasms/complications , Nephrectomy/methods , Nephrectomy , Pancreatectomy , Kidney Neoplasms/complications , Kidney Neoplasms
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