[Chemotherapy at the end of life: Uncommon clinical practice?] / Quimioterapia al final de la vida: ¿práctica clínica poco frecuente?

BACKGROUND: In view of the apparent increase in the aggressiveness of palliative chemotherapy, the purpose of this study was to find out and analyse the characteristics of cancer patients treated in our hospital, and who received chemotherapy near the end of life. PATIENTS AND METHODS: Retrospective, observational study in oncology-haematological patients who received chemotherapy between January 2016 and May 2017, and who died in that same period. Data on sociodemographic and clinical variables were collected. In order to determine the risk factors for receiving chemotherapy in the last month of life, a multivariate logistic regression model was developed and subsequently validated using "bootstrap" re-sampling techniques. RESULTS: A total of 293 patients who received chemotherapy during the study period died. The median time between the last cycle of chemotherapy and death was 52 (0-459) days. Chemotherapy was received in their last month of life in 98 (33.4% of patients. the multivariate analysis indicated that the low chemo-sensitivity of the tumour, the particular medical oncologist, and the fact of dying in the hospital setting, were associated with an increased risk of receiving chemotherapy in the last month of life. CONCLUSIONS: A worrying percentage of patients receive chemotherapy near the end of life. This makes it difficult to receive high-quality palliative care, as well as to die in a familiar environment. It is necessary to review the decision-making process in advanced cancer patients.

Conocimiento de los tratamientos en pacientes hospitalarios: herramienta necesaria para la seguridad asistencial / Knowledge of treatments in hospital patients: a necesary tool for safety in health care

Objetivo. Determinar la cantidad y calidad de información sobre medicamentos que reciben los pacientes atendidos en un hospital. Método. Estudio descriptivo transversal realizado durante febrero de 2011, mediante diseño de una encuesta y entrevista a 60 pacientes: 30 ingresados y 30 externos. Análisis descriptivo de los resultados: número y grado de conocimiento de los medicamentos respecto al tratamiento «real», analizado de forma global, por edad y por vía de administración. Resultados. En el grupo de pacientes ingresados se analizaron 234 medicamentos «reales». Según los resultados de la encuesta, 45/234 (19,2%; IC95%:14-25) fueron conocidos de forma adecuada por los pacientes. En los pacientes externos esta cifra ascendió a 29/42 (69,0%; IC95%:53-82). El 33,3% de los pacientes verificó su medicación antes de ser administrada o dispensada. Los pacientes ingresados conocían mejor los medicamentos administrados por vía oral: el 28,6% frente al 5,1% de los parenterales. El 45,3% de los ingresados y el 2,4% de los externos desconocían la medicación. La edad media de los pacientes con conocimiento nulo de su medicación fue de 68,5 años (DE=10,1) y tenían 8,7 medicamentos prescritos (DE=3,0). El 53,3% y el 93,3% de los pacientes ingresados y externos respectivamente, consideraban haber sido informado correctamente. El 96,7% dijeron estar satisfechos con la información recibida. Conclusiones. Los resultados obtenidos muestran un potencial de mejora importante respecto a la información que se da a los pacientes, especialmente ingresados, en el hospital. Informarles permitiría su participación como filtro ante posibles errores de medicación y como pieza necesaria para la mejora de la seguridad asistencial(AU)

Objective. To determine the quantity and quality of drug information that patients receive in hospital. Method. Cross-sectional study conducted in February 2011, by designing and conducting a structured questionnaire on 60 patients: 30 inpatients and 30 outpatients. Descriptive analysis of the results was performed including, number and level of knowledge of medication treatment versus the "real" one, globally analysed by age and route of administration. Results. A total of 234 drugs were analysed in the inpatient group. It was considered that 45/234 (19.2%;95% CI: 14-25) were known properly by patients. In outpatients, this rises to 29/42 (69.0%;95% CI: 53-82). One third (33.3%) of patients check the medication before it is administered or provided. Inpatients are more aware of orally administered drugs, they knew 28.6% vs 5.1% of parenteral treatments. Just under half (45.3%) of inpatients and 2.4% of outpatients completely unknown the medication. The average age of patients with no knowledge of their medication was 68.5 years (SD=10.1) and had 8.7 drugs prescribed (SD=3.0). A total of 53.3% of inpatients and 93.3% of outpatients, considered to have been properly informed. Most of patients (96.7%) were satisfied with the information received. Conclusions. The results show an opportunity for improvement in the information given to patients, particularly to inpatients. To inform them, would enable them to act as a filter to potential medication errors, and as a necessary part to improve the safety of care(AU)

[Knowledge of treatments in hospital patients: a necesary tool for safety in health care]. / Conocimiento de los tratamientos en pacientes hospitalarios: herramienta necesaria para la seguridad asistencial.

OBJECTIVE: To determine the quantity and quality of drug information that patients receive in hospital. METHOD: Cross-sectional study conducted in February 2011, by designing and conducting a structured questionnaire on 60 patients: 30 inpatients and 30 outpatients. Descriptive analysis of the results was performed including, number and level of knowledge of medication treatment versus the "real" one, globally analysed by age and route of administration. RESULTS: A total of 234 drugs were analysed in the inpatient group. It was considered that 45/234 (19.2%;95% CI: 14-25) were known properly by patients. In outpatients, this rises to 29/42 (69.0%;95% CI: 53-82). One third (33.3%) of patients check the medication before it is administered or provided. Inpatients are more aware of orally administered drugs, they knew 28.6% vs 5.1% of parenteral treatments. Just under half (45.3%) of inpatients and 2.4% of outpatients completely unknown the medication. The average age of patients with no knowledge of their medication was 68.5 years (SD=10.1) and had 8.7 drugs prescribed (SD=3.0). A total of 53.3% of inpatients and 93.3% of outpatients, considered to have been properly informed. Most of patients (96.7%) were satisfied with the information received. CONCLUSIONS: The results show an opportunity for improvement in the information given to patients, particularly to inpatients. To inform them, would enable them to act as a filter to potential medication errors, and as a necessary part to improve the safety of care.