Subject(s)
Lupus Erythematosus, Systemic/complications , Microsporum/isolation & purification , Skin/microbiology , Tinea Favosa/microbiology , Antifungal Agents/therapeutic use , Female , Glucocorticoids/therapeutic use , Humans , Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/drug therapy , Microsporum/drug effects , Middle Aged , Skin/drug effects , Skin/pathology , Tinea Favosa/diagnosis , Tinea Favosa/drug therapy , Treatment OutcomeABSTRACT
Porokeratosis is characterized clinically by annular plaques with a distinct peripheral keratotic ridge and histologically by the cornoid lamella. Porokeratosis with follicular involvement is rarely reported. To provide the basis of that follicular porokeratosis is a clinical variant or not. Biopsy was taken from three patients who were diagnosed porokeratosis. Routine stain was made and reviewed the literatures about well-documented cases of porokeratosis with follicular involvement. Porokeratosis with follicular involvement may have some clinical features: asymptomatic, erythematous, brownish or skin-color, less than 1 cm in the areas excluding palm and plantar, which commonly involved on middle-age. But there have still not enough proof as an independent clinical variant.
Subject(s)
Hair Follicle/pathology , Porokeratosis/pathology , Adult , Aged , Biopsy , Humans , Male , Middle AgedABSTRACT
BACKGROUND: Eccrine angiomatous hamartoma (EAH) is a rare benign cutaneous tumor characterized by the proliferation of eccrine glands and capillaries. OBJECTIVE: The aim of this study was to summarize the clinicopathological characteristics of EAH. METHODS: A retrospective chart review was performed on all patients diagnosed with EAH from 1977 to 2012 in the Union Hospital, Wuhan, P.R. China, and the clinicopathological features were compared with the cases reported in the literature. RESULTS: A total of 26 patients with EAH were identified. The male:female ratio was 1.2:1. EAH most commonly presents as a solitary (80.8%) plaque (50.0%) on the lower extremities (61.5%). Most patients presented with hyperhidrosis localizing to the lesion. Although most patients did not have major pain or anatomic deformity, one patient had severe pain as well as difficulty walking and moving, necessitating leg amputation. The histopathological findings showed typical features of EAH. CONCLUSION: EAH is a rare but characteristically benign skin hamartomatous condition. In rare occasions it can be associated with severe structural and functional impairment.
Subject(s)
Capillaries/pathology , Eccrine Glands/pathology , Hamartoma/pathology , Sweat Gland Neoplasms/pathology , Adolescent , Child , Child, Preschool , Female , Hamartoma/complications , Hamartoma/surgery , Humans , Hyperhidrosis/etiology , Infant , Infant, Newborn , Lower Extremity , Male , Pain/etiology , Retrospective Studies , Sweat Gland Neoplasms/complications , Sweat Gland Neoplasms/surgeryABSTRACT
The follicular hybrid is composed of more than two components of pilosebaceous unit. There are several studies of hybrid cyst, combination of trichilemmal and epidermoid cyst was the most frequently reported. In this paper, we reported one case of hybrid cyst composed of bullous pilomatricoma and epidermoid cyst. A 14-year-old girl was complaint of a solitary flesh-colored to erythematous nodule with flaccid appearance sized 3.2 × 1.8 cm in diameter on her right upper back for one year. The histologic findings showed there were edema and proliferation of capillaries in the superficial dermis, a cyst in the middle to deep dermis. There were laminated keratins in the cystic space. The cyst wall was composed of two different components, one was composed of epithelial cells containing of granular layer, and another consisted of basophilic cells, transient cells and shadow cells. The cyst not related with Gardner's syndrome. Hybrid cyst such as trichilemmal cyst, epidermoid and pilomatricoma cysts maybe have same clinical features or mimicking each others, but we can distinguish them from histopathology evaluation.
