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Ann Allergy ; 67(6): 615-8, 1991 Dec.
Article in English | MEDLINE | ID: mdl-1684273

ABSTRACT

Oral ebastine, 10 mg once daily for seven days, and placebo were compared as treatment for active perennial allergic rhinitis in 151 patients in a multicenter, randomized, double-blind trial. Ebastine treatment produced a significant reduction in the incidence and severity of most symptoms associated with perennial rhinitis. Tolerability was similar in the two treatment groups. The incidences of drowsiness and dry mouth were not more frequent in the patients treated with the active drug.


Subject(s)
Butyrophenones/therapeutic use , Histamine H1 Antagonists/therapeutic use , Piperidines/therapeutic use , Rhinitis, Allergic, Perennial/drug therapy , Adult , Butyrophenones/adverse effects , Butyrophenones/standards , Double-Blind Method , Female , Histamine H1 Antagonists/adverse effects , Histamine H1 Antagonists/standards , Humans , Male , Piperidines/adverse effects , Piperidines/standards , Time Factors
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