[Guidelines of the Spanish society of cardiology on requirements and equipment of the coronary care unit]. / Guías de práctica clínica de la Sociedad Española de Cardiología sobre requerimientos y equipamiento de la unidad coronaria.

The conceptual change and the dynamic care of patients observed in coronary care units, in recent years are reported. The coronary care unit is increasingly conceived as an intensive care unit for patients with acute or chronic cardiopathies with severe complications. Criteria for rational planification, functional and hierarchic organization and basic medical care arguments are established. The coronary care unit can not be considered as an isolated facility, but should rather be integrated in the cardiology department, under the direction of a cardiologist. The authors point out the basic, physical structure and characteristics of the equipment in the coronary care unit and the intermediate cardiac care unit, as well as the newly created chest pain units. Finally, we comment on the human resources (medical, nursing and administrative) and the criteria for admission and discharge in the coronary care unit.

[Vascular hyperreactivity to vasopressin in mild essential arterial hypertension]. / Hiperreactividad vascular a la vasopresina en la hipertensión arterial esencial moderada.

The aim of the present study was to evaluate the hemodynamic effects of arginine vasopressin (AVP) infusion in essential hypertension. To this end, 9 hypertensive patients and 10 normotensive controls were evaluated. After one hour rest, AVP was infused at a dosage of 0.5 and 2 ng/(kg/min), in 20 minutes periods. After AVP infusion, mean arterial pressure increased only in hypertensive patients (from 125.8 +/- 7 to 131.8 +/- 7, p less than 0.01 and to 135.6 +/- 6 mmHg, p less than 0.01). Peripheral vascular resistance was significantly increased in both groups during AVP infusion, although the percent increase was higher in hypertensive patients during the last period of infusion (18.3 +/- 10 versus 4.6 +/- 4, p less than 0.05). Cardiac index decreased in both groups during infusion, although this reduction was significantly higher in hypertensive patients than in healthy controls in the last period of infusion (-8.16 +/- 6 versus -1.8 +/- 4%, p less than 0.05). These results confirm that in essential hypertension there is an exaggerated pressor response to AVP infusion, suggesting that it is due to an increased vascular response to this hormone. The compensatory reduction of cardiac output and the inhibition of sympathetic nervous activity mediated through baroreceptor reflexes do not apparently play a role in this pressor response.