ABSTRACT
Solid pseudopapillary neoplasm of pancreas (SPN) is a rare entity; therefore proper diagnosis, evaluation and formulation of treatment protocols is difficult. A total of 14 cases were diagnosed and treated at our institute over a 10-year period (1992-2002). A retrospective study of all these cases was performed with respect to age group most frequently affected, sex ratio, common presenting symptoms and signs, investigative protocols, pathological features, treatment offered, outcome and prognosis. All the 14 patients were females, with a median age of 20 years (range 13-45 years). The commonest presenting symptom was abdominal pain. All these patients underwent surgical exploration; 13 patients underwent resection of the tumour. The average length of postoperative hospital stay was 10.3 days. Significant postoperative morbidity was seen in only one case. There was no postoperative mortality. All these patients who underwent resection were disease-free on follow-up ranging from 6 to 96 months (median 36 months).
ABSTRACT
Alveolar soft part sarcoma (ASPS) of the head and neck region has been a rarely reported entity. These lesions have a high propensity for distant metastasis. A retrospective study of the medical records at our institute, revealed thirty-eight cases of ASPS. Six of these were of primary head and neck origin. The article highlights the aggressive nature of the tumour and the need to arrive at a consensus on the treatment protocol.
Subject(s)
Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/therapy , Sarcoma, Alveolar Soft Part/pathology , Sarcoma, Alveolar Soft Part/therapy , Adolescent , Adult , Chemotherapy, Adjuvant , Child , Disease-Free Survival , Female , Head and Neck Neoplasms/mortality , Head and Neck Neoplasms/surgery , Humans , Male , Neoplasm Invasiveness , Neoplasm Metastasis , Neoplasm Recurrence, Local , Radiotherapy, Adjuvant , Retrospective Studies , Sarcoma, Alveolar Soft Part/mortality , Sarcoma, Alveolar Soft Part/surgerySubject(s)
Bone Cysts, Aneurysmal/diagnostic imaging , Adult , Female , Humans , Tomography, X-Ray ComputedABSTRACT
Inflammatory pseudotumors of the esophagus are uncommon. They pose diagnostic and therapeutic dilemmas, especially when located in the cervical esophagus. History and physical examination are rarely contributory. Routine radiologic investigations including barium swallow and computed tomography only raise the suspicion of a benign esophageal neoplasm. Esophagoscopy and biopsy do not provide a definite diagnosis, as these 'tumors' are frequently submucosal, unless they enlarge sufficiently to cause mucosal ulcerations. Endoscopic ultrasonography may accurately localize the tumor but is not diagnostic. Conservative surgical resection or debulking would be both diagnostic and therapeutic. Steroids, cyclophosphamide and low-dose radiotherapy may at best be considered second-line therapy. One such case of inflammatory pseudotumor of the cervical esophagus is presented and the relevant literature is reviewed. Our patient could not be diagnosed on preoperative investigations and required an esophagotomy with frozen section. We debulked the mass and the patient is asymptomatic 6 months after surgery.
Subject(s)
Esophageal Diseases/diagnosis , Esophageal Diseases/surgery , Granuloma, Plasma Cell/diagnosis , Granuloma, Plasma Cell/surgery , Adult , Biopsy, Needle , Esophagoscopy/methods , Female , Follow-Up Studies , Humans , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
Six children with a foreign body in the airway presented with progressive subcutaneous emphysema as a clinical feature. The aim of this report is to highlight this unusual clinical presentation of foreign body in the tracheobronchial tree. A peculiar arrangement of fascial planes in the neck, chest, and abdomen and an excessive pressure gradient at the alveolar level, facilitates extraalveolar migration of air in the subcutaneous tissue.
Subject(s)
Foreign Bodies , Respiratory System , Subcutaneous Emphysema/etiology , Child, Preschool , Female , Foreign Bodies/diagnosis , Foreign Bodies/physiopathology , Humans , Infant , Male , Retrospective Studies , Subcutaneous Emphysema/diagnosis , Subcutaneous Emphysema/physiopathologyABSTRACT
Urinary 17-ketosteroids were estimated in 29 lepromatous leprosy cases. Correlation between 17-ketosteroid values, histopathologic findings, and serum G.G.P.T. values is discussed. Low values of 17-ketosteroids were associated with definite leproma to liver indicating the value of liver damage to 17-ketosteroids. This was more marked in males than in females.
