Subject(s)
Electromyography , Lung Diseases, Obstructive/diagnosis , Neuromuscular Diseases/diagnosis , Adolescent , Adult , Female , Humans , Lung Diseases, Obstructive/complications , Lung Diseases, Obstructive/physiopathology , Male , Middle Aged , Neuromuscular Diseases/complications , Neuromuscular Diseases/physiopathologySubject(s)
Antilymphocyte Serum/administration & dosage , Autoimmune Diseases/drug therapy , Immunization, Passive , Immunosuppressive Agents/administration & dosage , Multiple Sclerosis/drug therapy , Plasmapheresis , Adrenocorticotropic Hormone/administration & dosage , Autoimmune Diseases/etiology , Autoimmune Diseases/immunology , Azathioprine/administration & dosage , Combined Modality Therapy , Cyclophosphamide/administration & dosage , Drug Evaluation , Glucocorticoids/administration & dosage , Humans , Methylprednisolone , Multiple Sclerosis/etiology , Multiple Sclerosis/immunology , Prednisolone/administration & dosageSubject(s)
Autoimmune Diseases/drug therapy , Azathioprine/therapeutic use , Cyclophosphamide/therapeutic use , Multiple Sclerosis/drug therapy , Myasthenia Gravis/drug therapy , Polyradiculoneuropathy/drug therapy , Prednisolone/therapeutic use , Autoimmune Diseases/etiology , Autoimmune Diseases/immunology , Drug Evaluation , Humans , Multiple Sclerosis/etiology , Multiple Sclerosis/immunology , Myasthenia Gravis/etiology , Myasthenia Gravis/immunology , Polyradiculoneuropathy/etiology , Polyradiculoneuropathy/immunologyABSTRACT
This is a survey of the experience in using corticosteroids, plasmapheresis, immunodepressants, hyperbaric oxygenation, laser and magnetotherapy in treating the infectious-allergic Guillain-Barre polyradiculoneuritis. The indications and counter-indications to individual techniques are presented as related to the character and course of the disease. The principles of interrelation of these techniques with other drug and physical therapies are discussed. The authors infer that combination of plasmapheresis with corticosteroids is the best for acute polyradiculoneuritis and prolonged use of maintenance doses of corticosteroids and immunodepressants, physical methods and gymnastics are recommended for chronic polyradiculoneuritis.
Subject(s)
Polyradiculoneuropathy/therapy , Adolescent , Adult , Anti-Inflammatory Agents/therapeutic use , Autoimmune Diseases/complications , Child , Electromagnetic Phenomena/therapeutic use , Female , Humans , Hyperbaric Oxygenation , Male , Middle Aged , Plasmapheresis , Polyradiculoneuropathy/etiology , Respiratory Tract Infections/complications , SteroidsSubject(s)
Polyradiculoneuropathy/diagnosis , Adolescent , Adult , Child , Electromyography , Female , Humans , Male , Middle Aged , Neurologic Examination , Polyradiculoneuropathy/therapyABSTRACT
The dynamics of the immunological parameters was studied in 17 patients with multiple sclerosis (MS) who received prednisolone therapy in combination with plasmacytapheresis. The authors measured the counts of blood lymphocytes, T- and B-cells, active, theophylline-sensitive and theophylline-resistant lymphocytes levels of IgA, IgM, and IgG, and of circulating immune complexes. Marked clinical improvement was attained in 9 patients, moderate improvement in 7 cases. The dynamics of the immunological parameters depended on the clinical characteristics of the disease. The best correction of immunological characteristics was observed in patients with exacerbation of the process, remittant course, and moderate severity of the disease. The authors discuss the variable reactivity of theophylline-sensitive lymphocytes to the treatment.
