ABSTRACT
Mice were exposed to helium-oxygen conditions (3.6 MPa, 5 sessions). Compression lasted for 6 h, isopression - 5 days, decompression - 18 h. The interval between sessions was 10 days. The present study has revealed that hyperbary increases the level of diene conjugates and shift bases in the erythrocyte membranes and plasma only after 1 and 3 sessions. Superoxide dismutase is suppressed after 3 and 5 sessions. Catalase activity remains unchanged. The effect of hyperbary on the induction of chromosome aberrations in bone marrow, cornea of the eye and germinal tissues has been studied. Bone marrow has been detected as more sensitive to hyperbary. Induction of aberrations in bone marrow cells has observed for 3 months.
Subject(s)
Chromosome Aberrations , Helium/pharmacology , Hyperbaric Oxygenation , Lipid Peroxidation/drug effects , Oxygen/pharmacology , Animals , Male , MiceABSTRACT
Prolonged helium-oxygen hyperbaric (pressure 3,6 MPa) increased diene conjugate and Schiff's base level in plasma and erythrocyte membranes of mice. In those conditions SOD and glucose 6-phosphate dehydrogenase activities were inhibited in erythrocytes. Lipid bilayer microviscosity and cholesterol content of erythrocyte membranes were increased.
Subject(s)
Erythrocytes/metabolism , Hyperbaric Oxygenation , Lipid Peroxidation , Animals , Cholesterol/blood , Erythrocyte Membrane/ultrastructure , Erythrocytes/enzymology , Glucosephosphate Dehydrogenase/blood , Lipid Bilayers/metabolism , Mice , Superoxide Dismutase/blood , Time FactorsABSTRACT
The clinical picture and treatment of postoperative parotitis in 31 patients are described. An early operation is recommended in case of the failure of conservative therapy. 22 patients were operated upon, 11 out of them recovered, and 11 died. Postoperative parotitis is directly responsible for the death of three out of them.
