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Ocul Immunol Inflamm ; 27(1): 2-6, 2019.
Article in English | MEDLINE | ID: mdl-29020486

ABSTRACT

PURPOSE: To report on ocular manifestations and visual outcomes of Thai patients with Behçet's Uveitis (BU). METHODS: We reviewed medical records of 50 BU patients (31 males and 19 females). Ocular manifestations, treatment modalities, complications, and visual outcomes were registered. RESULTS: Ocular involvement was bilateral in 76% of patients, resulting in 89 affected eyes. Panuveitis and posterior uveitis were the most common types. Retinal vasculitis was noted in majority of affected eyes and specifically arteritis was noticed in 32/57(56%). Most patients received combination therapy of systemic corticosteroids and immunosuppressive agents (azathioprine 72%). At final visit, VA ≤20/200 was observed in 25 affected eyes (28%). Risk factors for poor visual outcome were poor visual acuity at presentation (p < 0.001) and development of optic atrophy (p = 0.01). CONCLUSIONS: Typical ocular manifestations of Thai patients with BU consisted of bilateral uveitis affecting posterior eye segment with high rate of complications and frequent visual loss.


Subject(s)
Behcet Syndrome/complications , Retinal Vasculitis/complications , Uveitis, Posterior/complications , Visual Acuity/physiology , Adolescent , Adult , Age of Onset , Azathioprine/therapeutic use , Behcet Syndrome/drug therapy , Behcet Syndrome/physiopathology , Child , Drug Therapy, Combination , Female , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Immunosuppressive Agents/therapeutic use , Male , Middle Aged , Ophthalmoscopy , Retinal Vasculitis/drug therapy , Retinal Vasculitis/physiopathology , Retrospective Studies , Thailand , Tonometry, Ocular , Uveitis, Posterior/drug therapy , Uveitis, Posterior/physiopathology , Young Adult
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