[Association patterns of risk factors or cardiovascular disease, in a high risk Spanish population of 2,264 patients]. / Perfiles de asociación de factores de riesgo o enfermedad cardiovascular en población española de alto riesgo de 2.264 pacientes.

UNLABELLED: INTRODUCTION, BASES AND AIMS: The aim of this study is to present the different association patterns between cardiovascular disease risk factors and target organs lesion due to arterial hypertension (AH), and to establish the possible differences by gender and age, and compare our findings with the existing references in the medical literature. MATERIAL AND METHODS: Nationwide croo-sectional study with 2264 consecutive patients in the Outpatient Clinic of Internal Medicine 18 years of age or older and with high cardiovascular risk taken from the CIFARC (Integral Control of High Risk Cardiovascular Factors) study run by the SEMI (Spanish Internal Medicine Association) cardiovascular Risk Group. RESULTS AND DISCUSSION: We have obtained statistically significant correlations between: Raised levels of total cholesterol and LDL cholesterol, low HDL cholesterol and smoking habit. LDL cholesterol with Family History of early cardiovascular events (hereinafter FH) and ischemic cardiopathy. Low HDL cholesterol with FH. Smoking habit with FH. Left ventricular hypertrophy (LVH) with raised levels of proteinuria and creatinine, atheromatosis, retinopathy I-II, ischemic cardiopathy, and diabetic nephropathy. Ischemic cardiopathy with LVH, diabetic nephropathy, peripheral vascular disease (PVD) and age. Proteinuria with raised levels of creatinine, atheromatosis, retinopathy I-II, nephropathy and severe retinopathy. Retinopathy I-II with raised levels of creatinine, atheromatosis, nephropathy, PVD and severe retinopathy. Raised levels of creatinine with reduced levels of HDL cholesterol, proteinuria, atheromatosis, retinopathy I-II, nephropathy and PVD. FH inversely with age: patients with FH consult a doctor an average of three years earlier than patients who do not experience FH. Atheromatosis with LVH, raised levels of proteinuria and creatinine, retinopathy I-II, cerebrovascular disease, nephropathy, PVD and age. PVD with raised levels of creatinine, atheromatosis, retinopathy I-II, and ischemic cardiopathy. Cerebrovascular disease with atheromatosis, age and weight. Severe retinopathy with proteinuria, nephropathy, and retinopathy I-II. Diabetic nephropathy with raised levels of proteinuria and creatinine, atheromatosis, retinopathy I-II, ischemic cardiopathy, and severe retinopathy. Age with raised creatinine, atheromatosis, ischemic cardiopathy, and cerebrovascular disease. With respect to gender, we found differences in most of the studied variables. CONCLUSIONS: There exist different association patterns between the studied variables.

Perfiles de asociación de factores de riesgo o enfermedad cardiovascular en población española de alto riesgo de 2.264 pacientes / Asociation patterns of risk factors or cardiovascular disease, in a high risk Spanish population of 2,264 patients

Introducción, fundamentos y objetivos: El objetivo de este estudio es presentar los diversos perfiles asociativos entre factores de riesgo cardiovascular y lesión de órganos diana de la HTA, así como establecer las posibles diferencias entre sexos y por edades y comparar nuestros hallazgos con los reseñados en la bibliografía. Material y métodos: Estudio transversal de ámbito nacional con 2.264 pacientes consecutivos de las Consultas Externas de Medicina Interna, mayores de 18 años y con riesgo cardiovascular alto o muy alto, procedentes del Estudio CIFARC del Grupo de Riesgo Vascular de la SEMI. El tratamiento estadístico (Chi cuadrado, ANOVA y regresión líneal de Pearson) se ha realizado mediante el programa STATISTIX. Resultados y discusión: Hemos obtenido correlaciones estadísticamente significativas, entre: Colesterol total elevado y colesterol LDL, colesterol HDL bajo y tabaquismo. Colesterol LDL con Antecedentes Familiares Precoces de eventos cardiovasculares (AFP) y cardiopatía isquémica. Colesterol HDL bajo con AFP. Tabaquismo con AFP. HVI con elevaciones de proteinuria y creatinina, ateromatosis, retinopatía I-II, cardiopatía isquémica y nefropatía diabética. Cardiopatía isquémica con HVI, nefropatía diabética, enfermedad vascular periférica (EVP) y edad. Proteinuria con elevaciones de creatinina, ateromatosis, retinopatía I-II, nefropatía y retinopatía grave. Retinopatía I-II con elevaciones de creatinina, ateromatosis, nefropatía, EVP, y retinopatía grave. Elevaciones de creatinina con colesterol HDL descendido, proteinuria, ateromatosis, retinopatía I-II, nefropatía y EVP. AFP con la edad inversamente: Los pacientes con AFP acuden una media de tres años antes a consultas que los pacientes que no los presentan. Ateromatosis con HVI, elevaciones de proteinuria y creatinina, retinopatía I-II, enfermedad cerebrovascular, nefropatía, EVP y edad. EVP con creatinina elevada, ateromatosis, retinopatía I-II y cardiopatía isquémica. Enfermedad cerebrovascular con ateromatosis, edad y peso. Retinopatía grave con proteinuria, nefropatía y retinopatía I-II nefropatía diabética con elevaciones de proteinuria y creatinina, ateromatosis, retinopatía I-II, cardiopatía isquémica y retinopatía grave. Edad con creatinina elevada, ateromatosis, cardiopatía isquémica y enfermedad cerebrovascular. Respecto al sexo encontramos diferencias en casi todas las variables. Conclusiones: Existen diferentes perfiles asociativos entre las variables estudiadas

Introduction, bases and aims: The aim of this study is to present the different association patterns between cardiovascular disease risk factors and target organs lesion due to arterial hypertension (AH), and to establish the possible differences by gender and age, and compare our findings with the existing references in the medical literature. Material and methods: Nationwide croo-sectional study with 2264 consecutive patients in the Outpatient Clinic of Internal Medicine 18 years of age or older and with high cardiovascular risk taken from the CIFARC (Integral Control of High Risk Cardiovascular Factors) study run by the SEMI (Spanish Internal Medicine Association) cardiovascular Risk Group. Results and discussion: We have obtained statistically significant correlations between: Raised levels of total cholesterol and LDL cholesterol, low HDL cholesterol and smoking habit. LDL cholesterol with Family History of early cardiovascular events (hereinafter FH) and ischemic cardiopathy. Low HDL cholesterol with FH. Smoking habit with FH. Left ventricular hypertrophy (LVH) with raised levels of proteinuria and creatinine, atheromatosis, retinopathy I-II, ischemic cardiopathy, and diabetic nephropathy. Ischemic cardiopathy with LVH, diabetic nephropathy, peripheral vascular disease (PVD) and age. Proteinuria with raised levels of creatinine, atheromatosis, retinopathy I-II, nephropathy and severe retinopathy. Retinopathy I-II with raised levels of creatinine, atheromatosis, nephropathy, PVD and severe retinopathy. Raised levels of creatinine with reduced levels of HDL cholesterol, proteinuria, atheromatosis, retinopathy I-II, nephropathy and PVD. FH inversely with age: patients with FH consult a doctor an average of three years earlier than patients who do not experience FH. Atheromatosis with LVH, raised levels of proteinuria and creatinine, retinopathy I-II, cerebrovascular disease, nephropathy, PVD and age. PVD with raised levels of creatinine, atheromatosis, retinopathy I-II, and ischemic cardiopathy. Cerebrovascular disease with atheromatosis, age and weight. Severe retinopathy with proteinuria, nephropathy, and retinopathy I-II. Diabetic nephropathy with raised levels of proteinuria and creatinine, atheromatosis, retinopathy I-II, ischemic cardiopathy, and severe retinopathy. Age with raised creatinine, atheromatosis, ischemic cardiopathy, and cerebrovascular disease. With respect to gender, we found differences in most of the studied variables. Conclusions: There exist different association patterns between the studied variables