ABSTRACT
Anaphylaxis is a serious systemic hypersensitivity reaction that is usually rapid in onset and may cause death. It is characterised by the rapid development of airway and/or breathing and/or circulation problems. Intramuscular adrenaline is the most important treatment, although, even in healthcare settings, many patients do not receive this intervention contrary to guidelines. The Resuscitation Council UK published an updated guideline in 2021 with some significant changes in recognition, management, observation and follow-up of patients with anaphylaxis. This is a concise version of the updated guideline.
Subject(s)
Anaphylaxis , Anaphylaxis/diagnosis , Anaphylaxis/drug therapy , Emergency Treatment/adverse effects , Epinephrine/therapeutic use , Humans , Resuscitation/adverse effectsABSTRACT
The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline. These include: emphasis on repeating intramuscular adrenaline doses after 5â¯min if symptoms of anaphylaxis do not resolve; corticosteroids (e.g. hydrocortisone) no longer being routinely recommended for the emergency treatment of anaphylaxis; interventions for reactions which are refractory to initial treatment with adrenaline; a recommendation against the use of antihistamines for the acute management of anaphylaxis; and guidance relating to the duration of observation following anaphylaxis, and timing of discharge.
Subject(s)
Anaphylaxis , Food Hypersensitivity , Algorithms , Anaphylaxis/diagnosis , Anaphylaxis/etiology , Anaphylaxis/therapy , Epinephrine , HumansSubject(s)
Spinal Fusion , Tranexamic Acid , Adolescent , Anaphylaxis , Antifibrinolytic Agents , Blood Loss, Surgical , Humans , ScoliosisSubject(s)
Antifungal Agents/therapeutic use , Griseofulvin/therapeutic use , Scalp Dermatoses/diagnosis , Tinea Capitis/diagnosis , Child , Diagnosis, Differential , Diagnostic Errors , Female , Humans , Scalp Dermatoses/drug therapy , Scalp Dermatoses/microbiology , Tinea Capitis/drug therapy , Tinea Capitis/microbiologyABSTRACT
Pyomyositis of the obturator externus muscle is a rare cause of limp and hip pain in children. The exact etiology of the condition remains poorly understood, although a mechanism of transient bacteremia in association with increased muscle susceptibility has been proposed. This case describes the course of a rather than 1 child from presentation to diagnosis and demonstrates the requirement for magnetic resonance imaging in establishing a diagnosis.
